{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"technology_type":["ILLUMINA, Illumina HiSeq 2000 (ILLUMINA), Illumina HiSeq 2000"],"study_type":["Other"],"full_dataset_link":["https://ega-archive.org/studies/EGAS00001002404"],"host":["EGA"],"description":["EGA study EGAS00001002404"],"dataset_title":["Whole-genome sequencing (WGS) data of Gastric adenocarcinoma and adjacent normal tissues"],"category":["restricted"],"repository":["EGA"],"name_synonyms":["School Age Populations., study, School-Age Populations, stomach adenocarcinoma, Populations, Eastern Asian Peoples, adenocarcinoma of stomach, Genomes, Asian, Eastern Asian People, whole genome, East Asian, Population, Far East, Far East Asian, STAD, School-Age, East Asians, Far East Asians, People, Eastern Asians, School Age, Eastern Asian, School-Age Population, School Age Population, Chinese, Eastern, East, East Asian Peoples, Asian People"],"description_synonyms":["Biological Markers, Viral Marker, Materials, Surrogate Endpoints, Clinical Markers, Laboratory, Clinical Marker, Neoplasms, Benign Neoplasm, number, Biochemical, Endpoint, Gene, Prognostic Factors, Tumor, Serum, Malignant, presence, Surrogate End Points, Mutations, Surrogate Markers, Laboratory Markers, Biological, average, treatment, study, Biomarker, Prognoses, Clinical, Genetic, Genomes, Malignancy, Biological Marker, Tissue, genetic, Neoplasias, Immunologic Markers, Immune, Markers, malignant neoplasm, Viral Markers, Therapies, Malignancies, constitutitional genetic, Immunologic Marker, Biologic, Cancer, Tumors, Therapy, WGS, Viral, Malignant Neoplasm, Surrogate Endpoint, Serum Markers, familial, End Point, Biochemical Markers, Factor, Biologic Marker, Cistrons, Immune Marker, count in organism, disease management., Benign, MT, Marker, Surrogate End Point, Neoplasm, Genetic Materials, Genetic Material, Biologic Markers, Serum Marker, primary cancer, Factors, End Points, Surrogate, Prognostic, Endpoints, Benign Neoplasms, whole genome, Cancers, Immunologic, Laboratory Marker, malignant tumor, Treatments, Surrogate Marker, Malignant Neoplasms, Therapeutic, Biochemical Marker, Material, cardinality, Cistron, Treatment, inherited genetic, hereditary, Neoplasia, Immune Markers, Prognostic Factor"],"additional_accession":[]},"is_claimable":false,"name":"Comprehensive investigation of genome architecture of gastric adenocarcinoma with whole-genome sequencing in the Chinese population.","description":"In this study, we performed whole-genome sequencing (WGS) of 214 paired GC tumors and adjacent normal tissues to identify novel potential biomarkers. We extracted mutational signatures which induce somatic mutations and classified GC tumors into four groups with significantly different prognosis. Moreover, we observed copy number changes and structural variations frequently occurring in some cancer related genes. Our study covers a comprehensive genetic framework that can be used in clinical trials and treatment modalities in GC.","dates":{"updated":"2017-08-25 14:47:36"},"accession":"EGAS00001002404","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAD00001003269","EGAD00001003431","EGAD00001003392","EGAD00001003405","EGAC00001000010","EGAC00001000177"]}}