{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"study_type":["Other"],"full_dataset_link":["https://ega-archive.org/studies/EGAS00001002436"],"host":["EGA"],"description":["EGA study EGAS00001002436"],"dataset_title":["Evolution of four ER+ breast cancers"],"repository":["EGA"],"category":["restricted"],"name_synonyms":["mamma, mammary region, WGS, Single-Cell RNA, Single-Cell Transcriptome Analyses, Breasts, Single-Cell RNA-Seq, Single-Cell RNAseq, ScRNAseq, Single-Cell Transcriptome Analysis, Sc RNAseq, Analyses, Single Cell Gene Expression Profiling, Single-Cell Gene Expression Profiling, Lobe of breast, mammary part of chest, scRNA-seq, Lactiferous gland, ScRNA seq, Single Cell RNAseq, Single Cell RNA Seq, Transcriptome Analysis, RNA Seq, Single Cell Gene Expression Analysis, Brustdruese, Single-Cell RNA Seq, Transcriptome Analyses, glandula mammaria, Single-Cell, Single Cell Transcriptome Analysis, ScRNA-seq, Single-Cell Transcriptome., Single-Cell Transcriptome, Sc-RNAseq, single cell RNA sequencing, single-cell transcriptome sequencing, single-cell RNA-seq, Lobe of mammary gland, RNAseq, Seqs, RNA-Seq, Analysis, breast, Seq"],"description_synonyms":["mammary region, d230, Breasts, Single-Cell RNAseq, DNS, Sc RNAseq, (Deoxyribonucleotide)n, Single Cell Gene Expression Profiling, Neoplasms, Benign Neoplasm, Lactiferous gland, ascites, dTAFII250, ScRNA seq, RNA-seq., Tumor, EfW1, Malignant, glandula mammaria, Deoxyribonucleic acids, dmTAF[[II]]230, single-cell transcriptome sequencing, single-cell RNA-seq, Deoxyribonucleic Acid, dmTAF1, Taf230, Whole Transcriptome Shotgun Sequencing, Seqs, Analysis, Seq, TAF250, Taf200, thymus nucleic acid, dTAF[[II]]250, ScRNAseq, TFIID TAF250, Single-Cell Transcriptome Analysis, Genomes, Analyses, Malignancy, cel, Peritoneal effusion, cell, mammary part of chest, Double Stranded, Taf1p, Single Cell RNAseq, Deoxyribonucleic acid, Single Cell RNA Seq, Transcriptome Analysis, RNA Seq, ScRNA-seq, Neoplasias, dTAF250, malignant neoplasm, Clients, Malignancies, Double-Stranded DNA, RNA-Seq, ascitic fluid, (Deoxyribonucleotide)m, deoxyribonucleic acids, DNAn, TAF, Accumulation of fluid in the abdomen, Cancer, Tumors, mamma, ascites fluid, WGS, dTAF[[II]]230, TAF[[II]]250, Single-Cell RNA-Seq, Malignant Neoplasm, DNAn+1, Single-Cell Gene Expression Profiling, TAF200, scRNA-seq, l(3)84Ab, RNA-seq, BG:DS00004.13, Double-Stranded, TAFII-250, Single Cell Gene Expression Analysis, TAF250/230, Brustdruese, Client, Cell, Single-Cell, Single Cell Transcriptome Analysis, dTAF230, (Deoxyribonucleotide)n+m, Sc-RNAseq, TAFII250, single cell RNA sequencing, MT, Benign, p230, Lobe of mammary gland, Neoplasm, TAF[[II]]250/230, TFIID, ds-DNA, desoxyribose nucleic acid, Taf[[II]]250, Single-Cell RNA, Single-Cell Transcriptome Analyses, primary cancer, TAF[[II]]230, Lobe of breast, Benign Neoplasms, TAF[II]250, patient, whole genome, Cancers, CG17603, TAF[[II]], Single-Cell RNA Seq, Transcriptome Analyses, malignant tumor, Malignant Neoplasms, Single-Cell Transcriptome, metastatic, DmelCG17603, Taf250, Patient, SR3-5, RNAseq, ds DNA, Desoxyribonukleinsaeure, DNA, Neoplasia, breast, TAF230, TAF1"],"additional_accession":[]},"is_claimable":false,"name":"Subclonal evolution of four ER+ breast cancers determined by WGS and scRNA-Seq","description":"We analyzed the subclonal evolution of four ER+ breast cancers over 2-15 years using whole-genome sequencing (WGS) and single-cell RNA-Seq (scRNA-Seq). For each patient we analyzed 2-6 cancer samples, generally metastatic pleural effusions or ascites, by WGS, along with germline DNA. Two of the samples per patient were selected for single-cell RNA-Seq.","dates":{"updated":"2017-07-26 15:39:29"},"accession":"EGAS00001002436","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAD00001003303","EGAC00001000653"]}}