{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"study_type":["Transcriptome Analysis"],"full_dataset_link":["https://ega-archive.org/studies/EGAS00001002667"],"host":["EGA"],"description":["EGA study EGAS00001002667"],"dataset_title":["Single-Cell Atlas of Common Variable Immunodeficiency shows germinal center-associated epigenetic dysregulation in B cell responses"],"repository":["EGA"],"category":["restricted"],"name_synonyms":["Decreased immune function, Immune deficiency., immunodeficiency syndrome"],"description_synonyms":["hypogamma-globulinemia, World Wide Web., d230, B Cells, PhrB photolyase activity, COMMON VARIABL IMMUNODEF, Institution, RNA-seq  (transcriptome sequencing), Bursa-Dependent Lymphocytes, Shared, Deficiencies, dTAFII250, Immunoglobulin Deficiencies, photoreactivating enzyme activity, pigmented epithelium, EfW1, dmTAF[[II]]230, Common Variable Hypogammaglobulinemias, Sporadic hypogammaglobulinemia, Late-Onset Immunoglobulin Deficiencies, Immunodeficiency, Publication, dmTAF1, utilization, Taf230, Acquired Agammaglobulinemia, common variable immunodeficiency, Releasing, Twin, Variable Hypogammaglobulinemias, CVI - Common variable immunodeficiency, Whole Transcriptome Shotgun Sequencing, 3, Transcriptome Sequencing, stratum pigmentosa retinae, NUP96, Institutional, Web, CVID - Common variable immunodeficiency, Hypogammaglobulinemias, epithelium, TAF250, Total RNA Sequencing, Taf200, B-cell, MOS3, dTAF[[II]]250, deoxyribocyclobutadipyrimidine pyrimidine-lyase activity, Patient Discharge, TFIID TAF250, acquired agammaglobulinemia, PRECOCIOUS, cel, cell, Whole Transcriptome Sequencing, Common variable hypogammaglobulinaemia, pigmented retina, F23A5.3, Institute, Taf1p, Common Variable Hypogammaglobulinemia, DNA cyclobutane dipyrimidine photolyase activity, SUPPRESSOR OF AUXIN RESISTANCE 3, dTAF250, B lymphocyte, Discharge, Acquired Hypogammaglobulinemia, Common Variable Immune Deficiency, RNA Sequencing, COMMON VARIABLE IMMUNODEFIC, RNA-Seq, WWW, Acquired hypogammaglobulinaemia, TAF, F23A5_3, Late-Onset Immunoglobulin Deficiency, PRE, SINGLE, dTAF[[II]]230, TAF[[II]]250, use, Hypogammaglobulinemia, B Lymphocytes, statistics and numerical data, deoxyribonucleic cyclobutane dipyrimidine photolyase activity, TAF200, l(3)84Ab, Common variable agammaglobulinaemia, BG:DS00004.13, TAFII-250, TAF250/230, Common variable agammaglobulinemia, HTT Protein Measurement, Cell, acquired, Common variable agammaglobulinemia (disorder), dTAF230, Variable Hypogammaglobulinemia, common variable hypogamma-globulinemia, Released, registering_institution, TAFII250, MODIFIER OF SNC1, retinal pigment, HTTP, p230, Immunodeficiencies, Common, deoxyribonucleic photolyase activity, TAF[[II]]250/230, dipyrimidine photolyase (photosensitive), Huntingtin Protein, TFIID, numerical data, Discharge from Healthcare Facility, Release Determination, registering institution, Common Variable, retinal pigment layer, Acquired Hypogammaglobulinemias, Taf[[II]]250, Single Person, acquired hypogammaglobulinemia, Acquired, Discharged, CVAG, RPE, TAF[[II]]230, photolyase activity, Late-Onset, Information, Immunoglobulin deficiency, CVID, SHARED, WTSS, Bursa-Equivalent Lymphocyte, TAF[II]250, CG17603, TAF[[II]], late-onset, Release, p. pigmentosa retinae, Huntingtin Protein Measurement, Common variable hypogammaglobulinemia, phr A photolyase activity, common variable immune deficiency, INSTITUTION, DmelCG17603, Deficiency, Discordance, DNA-photoreactivating enzyme, Late Onset, Only, Taf250, B-Lymphocyte, SR3-5, Info, RNAseq, Whole-Transcriptome Sequencing, Common Variable Immunodeficiencies, WHOLE TRANSCRIPTOME SEQUENCING, Immunoglobulin Deficiency, Solitary, Late onset immunoglobulin deficiency, deoxyribonucleate pyrimidine dimer lyase (photosensitive), Single, Late-Onset Immunoglobulin, B-lymphocyte, Discordant, Total RNA-Seq, Alone, TAF230, TAF1"],"additional_accession":[]},"is_claimable":false,"name":"Immunodeficiency ","description":"We are doing single-cell RNAseq from B cells from monozygotic twins discordant for common variable immunodeficiency\n\n1) This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute please see http://www.sanger.ac.uk/datasharing/","dates":{"updated":"2022-02-23 14:52:16"},"accession":"EGAS00001002667","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAD00001008575","EGAC00001000205"]}}