EGAGenomicsTranscriptome Analysishttps://ega-archive.org/studies/EGAS00001003647EGAEGA study EGAS00001003647Mapping genetic variants underlying gene regulation in healthy intestinal cell types to identify novel IBD drug targetsMapping genetic variants underlying gene regulation in healthy intestinal cell types to identify novel IBD drug targets (2020-05-12)restrictedEGADrugs, Regulations, Products, Materials, Genetic, Bowel Diseases, Product, IBD, Pharmaceutic Preparations, Formal Social Control, drug, familial, Control, Gene, INFLAMM BOWEL DIS, INSDC_feature:gene, Controls, Cistrons, Social Controls, genetic, Social, Drug, Preparations, Inflammatory Bowel Diseases, drugs, Pharmaceuticals., Material, Social Control, medicine, Pharmaceutical, inflammatory bowel disease, psychogenic IBS, Pharmaceutical Product, Genetic Materials, Cistron, autoimmune bowel disorder, inherited genetic, regulation, Pharmaceutic, Preparation, Inflammatory, constitutitional genetic, Pharmaceutical Products, hereditary, Regulation, Formal Social Controls, Genetic Material, Pharmaceutical PreparationRibonucleic, d230, IL1BC, Meth, PhrB photolyase activity, DrIce, DrICE, CASP-1, CG7788, crice, dTAFII250, photoreactivating enzyme activity, pigmented epithelium, Chalk, EfW1, Publication., dmTAF[[II]]230, Structural, Publication, rectal part of digestive tract, dmTAF1, Taf230, Tina, Gene Products, Functional, 3, stratum pigmentosa retinae, NUP96, Il1bc, rectum, epithelium, Non Polyadenylated, RNA Gene Products, TAF250, terminal portion of intestine, Taf200, MOS3, Glass, dTAF[[II]]250, deoxyribocyclobutadipyrimidine pyrimidine-lyase activity, Biopsies, TFIID TAF250, PRECOCIOUS, cel, terminal section of digestive tract, cell, Comparative Genomics, PCE-2, pigmented retina, F23A5.3, Taf1p, IL-1BC, DNA cyclobutane dipyrimidine photolyase activity, SUPPRESSOR OF AUXIN RESISTANCE 3, Non-Polyadenylated RNA, dTAF250, Caspase-1 subunit p20, ICE, Ice, TAF, 10X sequencing, F23A5_3, PRE, terminal portion of large intestine, RNA, dTAF[[II]]230, TAF[[II]]250, Genomics, Caspase-1 subunit p10, iCE, ice, drice, caspase 3, ribose nucleic acid, Comparative, deoxyribonucleic cyclobutane dipyrimidine photolyase activity, ribonucleic acids, TAF200, l(3)84Ab, Rectums, RNS, BG:DS00004.13, 10x sequencing, CE-2, Functional Genomics, TAFII-250, TAF250/230, Cell, DmelCG7788, dTAF230, TAFII250, MODIFIER OF SNC1, retinal pigment, drIce, drICE, p230, yeast nucleic acid, Ribonukleinsaeure, deoxyribonucleic photolyase activity, TAF[[II]]250/230, dipyrimidine photolyase (photosensitive), TFIID, pentosenucleic acids, Ribonucleic acids, CES2A1, retinal pigment layer, Crystal, Taf[[II]]250, ribonucleic acid, Acid, RPE, TAF[[II]]230, photolyase activity, Non Polyadenylated RNA, P45, Non-Polyadenylated, IL-1 beta-converting enzyme, TAF[II]250, Ribonucleic Acid, Interleukin-1 beta-converting enzyme, intestinum rectum, CG17603, TAF[[II]], p. pigmentosa retinae, Interleukin-1 beta convertase, Speed, phr A photolyase activity, DmelCG17603, rectal sac, DNA-photoreactivating enzyme, Taf250, SR3-5, Drice, 3.4.22.36, p45, Structural Genomics, deoxyribonucleate pyrimidine dimer lyase (photosensitive), DRICE, TAF230, TAF1falseMapping genetic variants underlying gene regulation in healthy intestinal cell types to identify novel IBD drug targetsBiopsies from the terminal ileum and rectum of healthy individuals are digested on ice to single cells and processed for single-cell RNA-sequencing (10X Genomics and Illumina) This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/2020-08-25 08:31:20EGAS000010036479606EGAD00001006331EGAD00001006139EGAC00001000205