EGAGenomicsOtherhttps://ega-archive.org/studies/EGAS00001003648EGAEGA study EGAS00001003648Whole genome sequencing and genotyping of samples from TZPAR (Pare from Tanzania)Whole genome sequencing and genotyping of samples from BFMOS (Mossi from Burkina faso)Whole genome sequencing and genotyping of samples from TZWAS (Wasaamba from Tanzania)Whole genome sequencing and genotyping of samples from TZCHA (Chagga from Tanzania)Whole genome sequencing and genotyping of samples from CMBAN (Bantu from Cameroon)Whole genome sequencing and genotyping of samples from CMSBA (Semibantu from Cameroon)restrictedEGAAW488255, Policies, other disease, Understanding., human being, Materials, PhrB photolyase activity, HSN1E, NetrinA, number, D430049E23Rik, Goal, Remittent, Gene, photoreactivating enzyme activity, pigmented epithelium, presence, netrin, Human, Plasmodium Infections, Aim, Readability, AIM, Africa, Publication, Homo sapiens, diseases, Hek6, disease or disorder, Cek6, Ethnic Group, 3, diseases and disorders, stratum pigmentosa retinae, Low, NUP96, epithelium, Man, ENSMUSG00000074119, DNMT1, ERP, APUDoma, Erp, me75, Elkh, human disease, MOS3, Diversity, deoxyribocyclobutadipyrimidine pyrimidine-lyase activity, Genetic, Man (Taxonomy), Infections, DNMT1_HUMAN, PRECOCIOUS, Tyrosine-protein kinase receptor EPH-2, EK6, pigmented retina, F23A5.3, SAP-2, Sap-2, D17Mit170, Subsaharan Africa, T1, DNA cyclobutane dipyrimidine photolyase activity, SUPPRESSOR OF AUXIN RESISTANCE 3, genetic, non-neoplastic, API6, neuroendocrine tumour, 2.7.10.1, Solute carrier family 6 member 2, Etrp, Nationality, Fever, CT27014, NET1, SLC6A5, disorder, Homo sapiens disease, NAT1, netA, 10X sequencing, Nucleotide, Marsh, constitutitional genetic, plasmodiosis, CXXC finger protein 9, Marsh Fever, Paludism, Variation, F23A5_3, NET, Net, DNA MTase HsaI, DNA (cytosine-5)-methyltransferase 1, Genetic Variations, PRE, Elk, ELK, C130099E04Rik, cou, Variations, Neuronally-expressed EPH-related tyrosine kinase, Sub-Saharan Africa, deoxyribonucleic cyclobutane dipyrimidine photolyase activity, Modern, Plasmodium, DNMT, EPH tyrosine kinase 2, familial, disorders, Ethnic Groups, Diversities, SAP2, 10x sequencing, 9330129L11, medical condition, MCMT, neuroendocrine tumor, Tl3, Tl2, Cistrons, net, neuroendocrine neoplasm, count in organism, MODIFIER OF SNC1, Lr, retinal pigment, Norepinephrine transporter, DNA methyltransferase HsaI, Genetic Diversities, deoxyribonucleic photolyase activity, Infection, dipyrimidine photolyase (photosensitive), sequence, EPH-like kinase 6, condition, Genetic Materials, Sub-Saharan, retinal pigment layer, Genetic Material, nucleotides, CXXC9, ADCADN, RPE, UNQ203/PRO229, CT-2, Plasmodium Infection, photolyase activity, DNA (cytosine-5-)-methyltransferase 1, Nationalities, INSDC_feature:gene, Genetic Diversity, hEK6, Understanding, CG18657, CXXC-type zinc finger protein 9, human, primary structure of sequence macromolecule, p. pigmentosa retinae, disease, phr A photolyase activity, DmelCG18657, DNA-photoreactivating enzyme, EPHT2, Material, Modern Man, cardinality, Bra, Remittent Fever, Cistron, deoxyribonucleate pyrimidine dimer lyase (photosensitive), inherited genetic, hereditary, netrin A, CLEC2C, humans, m.HsaIComplete, Complete Genome, Whole Genome, Upper Volta, Whole, Nationality, Burkina Fasso, Complete Genome Sequencing, Genome Sequencing, Ethnic Group, Ethnic Groups, Nationalities, United Republic of Tanzania, Cameroons, United Republic of Cameroon, Republic of Cameron, Sequencing, Zanzibar, Dodoma, Dar es Salaam capital until 1996., Tanganyika.falseWhole genome sequencing of six ethnic groups from Burkina Faso, Cameroon, and TanzaniaWe conducted low-coverage (~10x) sequencing of six ethnic groups from three malaria-endemic countries in sub-Saharan Africa, with the aim of characterising genetic diversity and improving imputation performance for genotyped samples in these populations. This data is part of a pre-publication release and is available under managed access. Please see https://www.malariagen.net/data/terms-use/human-gwas-data for more information on MalariaGEN data access policies. The purpose of the project was to support the discovery and understanding of genetic variants that influence human disease. Specifically defined goals were: a. the discovery of single nucleotide variants at frequencies of 1% or higher in diverse populations, b. even more comprehensive discovery (variants down to frequencies of 0.1 - 0.5%) in functional gene regions, and c. discovery of structural variants, such as copy number variants, other insertions and deletions, and inversions, including sequence-level understanding of breakpoints.2019-08-26 17:29:04EGAS000010036489606EGAD00001005014EGAD00001005013EGAD00001005015EGAD00001005011EGAD00001005012EGAD00001005016EGAC00001001201