{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"study_type":["Cancer Genomics"],"full_dataset_link":["https://ega-archive.org/studies/EGAS00001004165"],"host":["EGA"],"description":["EGA study EGAS00001004165"],"dataset_title":["MCL NGS data","DNA methylation Arrays","Copy Number Arrays for study EGAS00001004165","Gene Expression Profiling for study EGAS00001004165"],"category":["restricted"],"repository":["EGA"],"name_synonyms":["Mantle-Zone Lymphoma, mantle cell, Lymphocytic, Acceptance, Centrocytic Small Cell, activation by organism of non-apoptotic programmed cell death in other organism, Mantle-Cell Lymphoma, stimulation by symbiont of host programmed cell death, hemolysin activity, Process, Mantle-Zone, Small-Cell Lymphomas, Processes, regulation by symbiont of host system process, Centrocytic Small-Cell, positive regulation by symbiont of host non-apoptotic programmed cell death, Centrocytic, Intermediate, causes, Small-Cell Lymphoma, Acceptance Processes, Diffuse, Mantle Cell Lymphoma., Small-Cell, Acceptance Process, Mantle Cell, lymphoma, Lymphocytic Lymphoma, Centrocytic Small-Cell Lymphomas, induction by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction, Poorly-Differentiated, Mantle-Zone Lymphomas, activation by symbiont of host programmed cell death, Lymphoma, causality, modulation by symbiont of host system process, Mantle Zone Lymphoma, Centrocytic Small-Cell Lymphoma, pathogenesis, Mantle-Cell Lymphomas, Diffuse Lymphocytic Lymphoma, Poorly Differentiated, Intermediate Differentiated, Behaviors, Lymphomas, Mantle-Cell, single-organism behavior"],"description_synonyms":["Mantle-Zone Lymphoma, mantle cell, Centrocytic Small Cell, d230, impact-a., number, Gene, dTAFII250, clefted, EfW1, Ximpact, presence, Mutations, dmTAF[[II]]230, dmTAF1, Taf230, Intermediate Differentiated, nodal4-A, Lymphomas, TAF250, xnr4, imprinted and ancient gene protein, Lymphocytic, Taf200, LRCC, dTAF[[II]]250, Gene Expressions, TFIID TAF250, Small-Cell Lymphomas, cel, cell, Taf1p, Small-Cell Lymphoma, Expressions, Diffuse, dTAF250, Mantle Cell, Poorly-Differentiated, Mantle Zone Lymphoma, Diffuse Lymphocytic Lymphoma, Expression, MCL, MCUL1, TAF, NODAL, dTAF[[II]]230, TAF[[II]]250, Mantle-Cell Lymphoma, subdivided, TAF200, Centrocytic, Point Mutations, Intermediate, l(3)84Ab, BG:DS00004.13, TAFII-250, TAF250/230, Cell, dTAF230, count in organism, TAFII250, Tg.413d, p230, TAF[[II]]250/230, TFIID, imprinted and ancient gene protein homolog, IMPACT, HLRCC, Mutation, Mantle-Cell, forked, Taf[[II]]250, CLECSF8, nodal4, divided, TAF[[II]]230, Mantle-Zone, HTX5, Centrocytic Small-Cell, common, TAF[II]250, septate, CG17603, TAF[[II]], Small-Cell, DmelCG17603, lymphoma, Lymphocytic Lymphoma, Centrocytic Small-Cell Lymphomas, Taf250, Mantle-Zone Lymphomas, SR3-5, Point, Lymphoma, cardinality, Centrocytic Small-Cell Lymphoma, nr4, Mantle-Cell Lymphomas, Poorly Differentiated, Mantle Cell Lymphoma, E430016J11Rik, RWDD5, TAF230, TAF1"],"additional_accession":[]},"is_claimable":false,"name":"Genomic and epigenomic insights into the origin, pathogenesis and clinical behavior of mantle cell lymphoma subtypes","description":"Mantle Cell Lymphoma can be subdivided into conventional (cMCL) and leukemic non-nodal MCL (nnMCL), which differ in the cell of origin, gene expression, biological characteristics and clinical evolution. Using genomic, epigenomic and transcriptomic data we identified common and particular alterations in the two subtypes, either point mutations, copy number alterations or structural variants some of them with prognostic impact.","dates":{"updated":"2020-05-20 10:51:46"},"accession":"EGAS00001004165","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAD00001006025","EGAD00010001841","EGAD00010001877","EGAD00010001842","EGAC00001001453"]}}