{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"study_type":["Cancer Genomics"],"full_dataset_link":["https://ega-archive.org/studies/EGAS00001004672"],"host":["EGA"],"description":["EGA study EGAS00001004672"],"dataset_title":["Whole genome sequencing of the healthy breast"],"repository":["EGA"],"category":["restricted"],"name_synonyms":["Human, mamma, average, mammary region, Breasts, human being, Man (Taxonomy), Homo sapiens, breast., Modern Man, Lobe of mammary gland, Modern, Lobe of breast, mammary part of chest, Lactiferous gland, Man, Brustdruese, human, glandula mammaria"],"description_synonyms":["mammary region, primary breast cancer, malignant tumor of the breast, Breasts, lifespan, determination, P62, Neoplasms, Lactiferous gland, mammary neoplasm, Mammary Cancers, Human Mammary Neoplasms, sci, Tumor, glandula mammaria, Pregnancies, Human, Mutations, Relative, Breast Malignant Tumor, PREGN, \"neoplasm of breast (disorder)\" EXACT [SNOMEDCT_2005_07_31:126926005], Breast Tumor, HOW, How, \"mammary tumor\" EXACT [CSP2005:2016-0671], Mood, breast tumor, cancer of the breast, l(3)j5D5, 24B, average, BC, study, Mammary Neoplasms, malignant neoplasm of breast, Human Mammary, Complete, Whole Genome, l(3)s2612, entire lifespan, Mammary Neoplasm, entire life cycle, Moods, Mammary Carcinoma, mammary part of chest, Complete Genome Sequencing, stru, Human Mammary Carcinomas, l(3)S053606, CG10293, Sequencing, Cancer of the Breast, l(3)j5B5, cancer of breast, Malignant Tumor of Breast, Mammary, Mammary Cancer, Whole, DmelCG10293, Breast, mammary cancer, mammary tumor, Breast Malignant Neoplasms, Tumors, Cancer, mamma, Breast Carcinoma, Human Mammary Neoplasm, Carcinoma, 0904/17, Breast Carcinomas, \"breast neoplasm\" EXACT [MTH:120], clone 2.39, RnBP, Affects, Genome Sequencing, GlcNAc 2-epimerase, qkr, \"breast tumor\" EXACT [NCI2004_11_17:C2910], Brustdruese, l(3)S090417, Breast Malignant Neoplasm, N-acetyl-D-glucosamine 2-epimerase, Complete Genome, epithelial, Mammary Carcinomas, SZ1, Lobe of mammary gland, KH93F, RENBP, chemical analysis, Neoplasm, Human Mammary Carcinoma, NOS, Malignant Neoplasm of Breast, epitheliocyte, Relative Risk, who, Carcinomas, Breast Neoplasm, Risk, Gestation, Relative Risks., life, Risks, Lobe of breast, Who/How, Cancers, \"mammary neoplasm\" RELATED [], AGE, breast cancer, Breast Tumors, Breast Cancer, Breast Malignant Tumors, qkr[93F], renin-binding protein, anon-EST:Liang-2.39, Cancer of Breast, assay, cancer, breast"],"additional_accession":[]},"is_claimable":false,"name":"mutational landscape of normal human breast","description":"The accumulation of somatic mutations in the healthy breast throughout life and pregnancy is poorly understood. Here we describe whole genome sequencing analysis of epithelial and stromal compartments from the normal breast. We aimed to study how pregnancy and age affect both the mutational burden and the clonality of the healthy breast, and the subsequent implications on breast cancer risk.","dates":{"updated":"2023-07-27 11:02:42"},"accession":"EGAS00001004672","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAD00001006402","EGAC00001001742"]}}