{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"study_type":["Other"],"full_dataset_link":["https://ega-archive.org/studies/EGAS00001005064"],"host":["EGA"],"description":["EGA study EGAS00001005064"],"dataset_title":["Mutational analysis of an oligoprogressive sarcomatoid hepatocellular carcinoma treated with an immune checkpoint inhibitor."],"repository":["EGA"],"category":["restricted"],"additional_accession":[]},"is_claimable":false,"name":"Mutational analysis of an oligoprogressive sarcomatoid hepatocellular carcinoma treated with an immune checkpoint inhibitor.","description":"In this study, we describe a patient diagnosed with metastatic sarcomatoid hepatocellular carcinoma that showed a remarkable tumor response to Nivolumab, an immune checkpoint inhibitor, followed by an oligoprogression. Molecular analysis of the primary tumor in addition to a bone and brain metastasis was performed and we were able to identify driver genetic alterations indicating a possible role in the tumorigenesis process besides some alterations that may be associated with metastasis.","dates":{"updated":"2022-07-19 12:06:46"},"accession":"EGAS00001005064","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAD00001006982","EGAC00001001976"]}}