EGAGenomicsCancer Genomicshttps://ega-archive.org/studies/EGAS00001005660EGAEGA study EGAS00001005660Somatic mutant selection is altered by prior NOTCH1 mutation in ageing esophageal epitheliumEGArestrictedfalseMutant clone mapping in oesohagus restricted baitWe will use targeted exome sequencing to examine normal appearing oesophageal epithelium to determine the mutational burden. DNA will be extracted from epithelia of a defined size and we will overlay positional information from the epithelial pieces to give clone maps over a wide area.2024-10-16 12:35:42EGAS000010056609606EGAD00001015256EGAC00001000000