EGAGenomicsOtherhttps://ega-archive.org/studies/EGAS00001005756EGAEGA study EGAS00001005756Cancer-independent, second somatic NF1 mutation of normal tissues in neurofibromatosis type 1EGArestrictedMummified Fetus, WGS, thymus nucleic acid, fetus stage, DNS, (Deoxyribonucleotide)n, Tissues, embryo late stage, Deoxyribonucleic acids., DNAn+1, Tissue, Double Stranded, Deoxyribonucleic acid, Double-Stranded, Fetus, Structures, Fetal Tissue, Structure, embryo late growth stage, Mummified, (Deoxyribonucleotide)n+m, Retained Fetus, Fetuses, Fetal Tissues, Deoxyribonucleic Acid, Fetal, fetal stage, ds DNA, Desoxyribonukleinsaeure, Retained, Fetal Structure, Double-Stranded DNA, (Deoxyribonucleotide)m, DNA, deoxyribonucleic acids, DNAn, ds-DNA, desoxyribose nucleic acid, Fetal Structures, fetusl(1)Ab, Act5c, l(1)G0010, 2410041A17Rik, methionine aminopeptidase activity, ACTG, ACTE, ACT5C, CG12051, fs(1)M34, Serpin A3, Development, Bach, csp2, Act5, l(1)G0420, Human, protrusion, Mutations, DmelCG12051, l(1)G0025, Fetuses, HEL-176, CG4601, 2, Cell growth-inhibiting gene 24|25 protein, DmF2, Fs(3)Hor, familial adenomatous polyposis, MAP, peptidase M activity, adenomas, lod, A, C, rabGAPLP, act5C, L-methionine aminopeptidase activity, DmelCG2684, Complete, cyt5C, Whole Genome, DHO, Tissues, BRWS2, familial adenomatous polyposis 2, Tissue, Complete Genome Sequencing, CG18572, RabGAP-5, NTef2, Structures, Structure, Sequencing, Mummified, fs(1)829, autosomal recessive multiple colorectal adenomas, Act42a, anon-EST:fe2D2, 1700027G07Rik, Fetal, act 42A, RUSC3, DmelCG18572, Whole, Ac5C, CG4027, ACT, Act, Fetal Structure, T11, Act-5C, Cte-II, l(1)G0177, 42A, CPS, l(1)G0330, anatomical protrusion, MUTYH-Associated Polyposis, Actin/BAP47, CTE-II, AACT, dJ393D12.2, MYH-associated polyposis, CTE-IIa, autosomal recessive familial adenomatous polyposis, Genome Sequencing, act, Maps, Ach1, hBACH, ACH1, LACH1, Cell, act42A, Fs(3)Sz11, GIG25, CAD, Complete Genome, Su(b), Alpha-1-antichymotrypsin His-Pro-less, beta-actin, AFFX-Dros-ACTIN_M_r_at, GIG24, M32055, DFNA26, Act42, actin, spine., simple tissue, ACTA3, LACH, Fetal Structures, GAT, DFNA20, autosomal recessive, Mummified Fetus, l(1)G0079, RUTBC3, DmelCG4027, PYR1, l(1)G0117, VSCM, act 5C, Actin, MYH-Associated Polyposis, Fetus, Lds, Fetal Tissue, beta-actin/Bap47, early, RABGAP5, l(1)G0486, l(1)G0245, Retained Fetus, actin5C, l(1)G0009, Fetal Tissues, ACTL3, Lach1, Horka, multiple colorectal, CG2684, Fs(3)Horka, DRORUD, MAP syndrome, BAP47, Retained, ACTSG, BACH, Bap47, Actin5C, FAP2, colorectal adenomatous polyposisfalseWGS 11pcw fetus hdbr 15951 DNAMutations act as molecular barcodes detailing the origins of the cells that compose a tissue. To generate a high resolution map of the clonal origins and migration of cells during early human development, we will perform whole genome sequencing across the extensively sampled tissues of fetuses. Furthermore, the somatic mutations will reveal in utero mutational processes.2024-09-04 11:46:36EGAS000010057569606EGAD00001015398EGAC00001000000