{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"study_type":["Cancer Genomics"],"full_dataset_link":["https://ega-archive.org/studies/EGAS00001005840"],"host":["EGA"],"description":["EGA study EGAS00001005840"],"dataset_title":["RNA-seq samples","RP1759 AYA sarcoma methylation array","WES normal samples","WES tumor samples"],"category":["restricted"],"repository":["EGA"],"description_synonyms":["Teenager, Pilot, Bones and Bone Tissue, Bru, year, rasGAP, Female Adolescents, Male, Raw, RNA Sequence Determination, Across, Sequence Determination, adult stage, RNA Sequence, Grade (high/low), Activated, PILOT, Youths, 10538, YEAR, OBJPRIM, Tumor, GAP1, osteogenic tissue, GADPH, Bone and Bone, SOFT TISSUE, CG8893, gap1, Initials, analysis, Project, PKWS, Whole Transcriptome, Transcriptome Sequencing, Activate, Analysis, grade, FBgn 32821, HISTOLOGY_GRADE, adult, Obtained, European Organization for Research and Treatment of Cancer, Bone Tissues, Adolescence, Svc, BG, Histopathology Grade, Analyses, Determination, Molecular, Initial Usage, Complete Exome Sequencing, Gapd, Whole Transcriptome Sequencing, matching, Tissue, Matched, mip, Female, Adult, Sequence Determinations, Adolescents, Bulgaria, a, Pilot Project, d-CdGAPr, grading, Submission, primary objective, CM-AVM, Condyles, Analyzed, Year, Malignancies, Male Adolescent, Teens, Submit, DmelCG8893, Bony Apophyses, EGR-3, Initial, Bridge-1, Tumors, Female Adolescent, High-Grade Sarcoma, no evidence of disease, Tumor Grade, Determined, FASTQ, no complaints, pediatric, Recruitment, Exome, Republic of Bulgaria, FASTQ Format, Teenagers, RASA, First, Collected, tumor grade, Determinations, Years, EORTC, Young Adults, Benign, BGR, Aviators, RENBP, High Grade Sarcoma, sxt, Obtain, YEARS, Adolescent, GAP, Gap, SOFT TIS, p120RASGAP, Adults, Karnofsky Performance Status 100, Bridge, Co-Pilots, child, Empiric, Ras-GAP, Complete Transcriptome, CG10538, Projects, portion of bone tissue, histological_grade, Benign Neoplasms, gap, Condyle, Teen, Initial Adverse Event and Product Problem Report, AGE, Malignant Neoplasms, recruitment (subjects), Submitted, Young, Histopathologic Grade, Bony, Patient, bone, Ras p21 protein activator, Pilot Study, Whole Exome Sequencing, Co Pilot, pairing, Bony Apophysis, other neoplasm, Transcriptome Sequencings, Bone, Elderly, Soft Tissue, Soft Tissue Route of Administration, soft tissue, young adult, 100: Normal, Complete Exome, Australia-Modified Karnofsky Performance Status 100, GAPDH II, years, Neoplasms, Traverse, Benign Neoplasm, DNA methylation profiling., GTPase-activating protein, Gapdh13F, Analytical, Determine, Malignant, BULGARIA, Northern Europe, Collected Value, Initial Adverse Event Report, Studies, Co-Pilot, Del(8)44H, Southern Europe, juvenile, Pediatric, portion of blood, study, WES, Complete, Exome Sequencings, Activation, ANALYSIS, Malignancy, RasGAP, Tissues, GA3PDH, Gap 1, GAPDH2, Grading, Sequencing, Study, Neoplasias, juvenile stage, Whole Exome, Gapdh-2, Tumor_Grade, COLLECTING, Poorly Differentiated or Undifferentiated Sarcoma, RNA Sequence Analyses, Initial Product Problem Report, Clients, Whole, histological grade, CG6721, RNA Sequencing, Apophysis, Cancer, Sequence Analyses, data, RNA, Apophyses, Complete Exome Sequencings, Malignant Neoplasm, whole blood, RnBP, RNA Sequence Determinations, vertebrate blood, Matching, Performance Status 100, GlcNAc 2-epimerase, Male Adolescents, Trial Primary Objective, RASGAP, Client, Collecting, Bones and Bone, Exome Sequencing, N-acetyl-D-glucosamine 2-epimerase, Empirical, initials, Youth, Grade, Gapdh, Western Europe, Neoplasm, Newly Diagnosed, rI533, bones, activate, Collection, p120GAP, GAPDH, Cross, osseous tissue, DmelCG6721, Col4a-1, Complete Transcriptome Sequencing, INITIAL, Aviator, Match, DmelCG10538, Childhood, Cancers, One Hundred, Bones, CMAVM, February, Pairing, Annum, mineralized bone tissue, Lansky Performance Status 100, Bone Tissue, Histologic Grade, RNA Sequence Analysis, renin-binding protein, 100, calcium tissue, bone organ, Feasibility, Neoplasia, tumor_grade, Pilot Studies"],"name_synonyms":["Connective Tissue Sarcoma, Malignant Soft Tissue Tumor, MAL NEO SOFT TISSUE LEG, sarcoma, Sarcoma of the Soft Tissue and Bone, Mesenchymal tumor, MAL NEO SOFT TISSUE NEC, malignant, Spindle Cell Sarcomas, Malignant neoplasm of connective and other soft tissue of lower limb, Malignant neoplasm of connective and other soft tissue of thorax, Malignant neoplasm of other specified sites of connective and other soft tissue, [M]Sarcoma NOS, site unspecified, Sarcoma of the Soft Tissue, Malignant neoplasm of connective and other soft tissue, unspecified, Soft Tissue Sarcoma, Sarcoma of Soft Tissue, including shoulder, Epithelioid Sarcomas, Malignant tumour of soft tissue, MAL NEO SOFT TISSUE HEAD, Soft tissue tumour, Malignant neoplasm of soft tissue, [M]Sarcoma NOS (morphologic abnormality), NOS, tumour of soft tissue and skeleton, Malignant mesenchymal tumour, Sarcoma of Soft Tissue and Bone, MAL NEO SOFT TIS PELVIS, Epithelioid, Malignant neoplasm of connective and other soft tissue of upper limb, Sarcomas, Malignant Tumor of the Soft Tissue, MAL NEO SOFT TIS ABDOMEN, Malignant neoplasm of connective and other soft tissue (disorder), Malignant neoplasm of connective and other soft tissue of head, MAL NEOPL TRUNK NOS., Spindle Cell, MAL NEO SOFT TISSUE NOS, including hip, MAL NEO SOFT TIS THORAX, and neck, Soft Tissue Sarcomas, Malignant neoplasm of connective and other soft tissue of abdomen, Malignant neoplasm of connective and other soft tissue of trunk, tumor of soft tissue and skeleton, Malignant Soft Tissue Neoplasm, Sarcoma, no ICD-O subtype, Malignant neoplasm of soft tissue (disorder), no ICD-O subtype (morphologic abnormality), Epithelioid Sarcoma, Malignant tumor of soft tissue, Malignant Neoplasm of the Soft Tissue, face, Malignant neoplasm of connective and other soft tissue of pelvis, Spindle Cell Sarcoma, Soft Tissue, connective and soft tissue neoplasm, MAL NEO SOFT TISSUE ARM"],"additional_accession":[]},"is_claimable":false,"name":"SPECTA RP-1759-AYA Sarcoma cohort","description":"EORTC-SPECTA RP1759 study focuses on cancers in adolescent and young adult (AYA), age 12 to 29 years. This study explicitly recruited AYA patients and therefore collected empirical data to bridge the molecular gap between pediatric and adult oncology.\nThe initial pilot study, activated in February 2019 across Europe, aimed to recruit 100 AYA patients (aged 12-29 years) with newly diagnosed or relapsed high-grade gliomas and high-grade bone and soft tissue sarcomas. The primary objective of the pilot is to determine feasibility and recruitment rates.\nHere we submit the data from patients with newly diagnosed, recurrent intermediate or high-grade sarcoma that were collected and analyzed during the study. More specifically, we submit raw FASTQ files obtained from whole exome sequencing (WES) of matching tumor and blood samples, tumor RNA sequencing and DNA methylation profiling.","dates":{"updated":"2022-03-23 14:08:53"},"accession":"EGAS00001005840","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAD00001008394","EGAD00001008405","EGAD00010002275","EGAD00001008393","EGAC00001001818"]}}