{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"study_type":["Other"],"full_dataset_link":["https://ega-archive.org/studies/EGAS00001006242"],"host":["EGA"],"description":["EGA study EGAS00001006242"],"dataset_title":["RNA-seq explants chondrocytes"],"repository":["EGA"],"category":["restricted"],"name_synonyms":["RNA, Ribonucleic, human being, Arthritides, ribose nucleic acid, Modern, Alpha-dystrobrevin-associated MAGE Protein, ribonucleic acids, Iodopanoic, RNS, chondrogenic tissue, Iodopanoic Acid, MAGE-E1 antigen, Human, Osteoarthrosis Deformans, Homo sapiens, osteoarthrosis and allied disorder, yeast nucleic acid, Osteoarthritides, Cholevid, Ribonukleinsaeure, cartilages, DAMAGE, Hepatocellular carcinoma-associated protein 1, Gene Products, pentosenucleic acids, Ribonucleic acids, 4, 6-triiodo-, Iopanoic., Iopagnost, Osteoarthrosis, Non Polyadenylated, Man, Benzenepropanoic acid, Telepaque, Cartilages, RNA Gene Products, Osteoarthroses, Osteoarthritis, degenerative arthritis, ribonucleic acid, Acid, portion of cartilage tissue, Man (Taxonomy), Polognost, Arthritis, RGD1560259, Non Polyadenylated RNA, Degenerative Arthritides, osteoarthrosis, Non-Polyadenylated, Ribonucleic Acid, AI847422, cartilage tissue, hypertrophic arthritis, human, Non-Polyadenylated RNA, degenerative joint disease, Degenerative polyarthritis, cartilage, Degenerative, HCA1, Degenerative joint disease, Modern Man, Arthrosis, 3-amino-alpha-ethyl-2, Hypertrophic arthritis, Arthroses, Degenerative Joint Disease, mMage-e1, Degenerative Arthritis, Elderly, degenerative, cartilaginous tissue"],"description_synonyms":["inhibitors, Transplant Donor, human being, HiSeq X Ten, Data Set, TJA, Transplant Donors., Modern, Transplant, Alpha-dystrobrevin-associated MAGE Protein, Iodopanoic, Semen Donors, inhibitor, RNA-seq, Client, Iodopanoic Acid, chondrogenic tissue, MAGE-E1 antigen, Human, Homo sapiens, Cholevid, cartilages, DAMAGE, Hepatocellular carcinoma-associated protein 1, Whole Transcriptome Shotgun Sequencing, 4, 6-triiodo-, Donor, Donors, Iopagnost, Benzenepropanoic acid, Telepaque, Man, Cartilages, antagonists, study, Acid, portion of cartilage tissue, Polognost, Man (Taxonomy), Organ Donor, RGD1560259, total joint replacement surgery, Tissue, inhibiteur, joint replacement surgery, AI847422, cartilage tissue, human, Semen Donor, joint replacement, Iopanoic, Semen, inhibidor, cartilage, antagonists and inhibitors, Patient, HCA1, Clients, Modern Man, 3-amino-alpha-ethyl-2, Tissue Donor, Ovum Donor, mMage-e1, Ovum, Ovum Donors, Organ Donors, Elderly, cartilaginous tissue, Organ"],"additional_accession":[]},"is_claimable":false,"name":"RNA-sequencing of mechanical stress induced osteoarthritis-like damage in aged human cartilage explants treated with the anti-deiodinase iopanoic acid","description":"The current study aimed to confirm chondroprotective effects of the D2 inhibitor iopanoic acid (IOP) in an ex vivo aged human osteochondral explant model in which injurious mechanical stress is applied to inflict OA-like damage. This dataset contains RNA-seq (Illumina HiSeq X ten) of osteochondral explant cartilage from aged human patients that underwent a joint replacement surgery due to OA (N=10 donors; n=21 explants).","dates":{"updated":"2022-05-11 09:32:43"},"accession":"EGAS00001006242","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAD00001008752","EGAC00001001619"]}}