{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"study_type":["Cancer Genomics"],"full_dataset_link":["https://ega-archive.org/studies/EGAS00001006913"],"host":["EGA"],"description":["EGA study EGAS00001006913"],"dataset_title":["Clinical utility of combined low-pass whole genome and targeted sequencing in liquid biopsies for diagnosis and monitoring of pediatric solid tumors"],"repository":["EGA"],"category":["restricted"],"additional_accession":[]},"is_claimable":false,"name":"Clinical utility of combined low-pass whole genome and targeted sequencing in liquid biopsies for diagnosis and monitoring of pediatric solid tumors","description":"We designed a liquid biopsy (LB) platform employing Low-Pass Whole Genome Sequencing (LP-WGS)\nand targeted sequencing of cell-free (cf) DNA isolated from plasma for detecting genome-wide copy\nnumber alterations and targeted gene fusions in pediatric solid tumors. A total of 143 plasma samples\nwere analyzed from 19 controls (patients with non-oncologic diagnoses) and 73 patients, including 44\nwith bone or soft tissue sarcomas, 12 with renal tumors, 10 with germ cell tumors, 5 with hepatic\ntumors, and 2 with thyroid tumors.","dates":{"updated":"2023-01-24 15:23:33"},"accession":"EGAS00001006913","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAD00001009972","EGAC00001003052"]}}