EGAGenomicsOtherCOVID-192019 novel coronavirus infectionSARS-CoV-22019-nCoV infectionsevere acute respiratory syndrome coronavirus 2coronavirus disease 2019SARS-coronavirus 2https://ega-archive.org/studies/EGAS00001007003EGAEGA study EGAS00001007003Genotyping_data_totalEGArestrictedmyeloid cell surface antigen CD33, COVID19, Disease, siglec-3, Coronavirus Disease 19, β-CoV, beta-CoV, COVID-19, 2019-nCoV Infections., SARS-CoV-2, Virus Infection, COVID-19 Virus Diseases, 2019 novel coronavirus, AW259686, cd206, sCD163, 2019 Novel Coronavirus Disease, SARS-CoV-2 Infections, 2019 nCoV Infection, COVID 19 Virus Infection, C-type lectin domain family 13 member D-like, Virus Disease, CD33, 2019 nCoV Disease, sialic acid-binding Ig-like lectin 3, COVID-19 Virus Disease, 2019-nCoV Infection, MR, 2019-nCoV Disease, SARS CoV 2 Infection, p67, Infection, Severe Acute Respiratory Syndrome Coronavirus 2 Infection, MMR, Coronavirus, macrophage mannose receptor 1-like protein 1, COVID-19 Virus Infections, β-coronavirus, 2019-nCoV, COVID 19 Pandemic, Soluble CD163, CLEC13DL, M130, β-CoVs, betacoronavirus, Disease 2019, Pandemic, clec13d, COVID-19 Virus Infection, Coronavirus Disease 2019, mmr, severe acute respiratory syndrome coronavirus 2, Coronavirus Disease-19, gp67, COVID-19 Pandemics, SARS-CoV-2 Infection, COVID-19 Pandemic, beta-CoVs, SARS-coronavirus 2, MRC1L1, SIGLEC-3, CD163, COVID-19 Virus, CLEC13D, 2019 Novel Coronavirus Infection, 2019-nCoV Diseases, CD206, SIGLEC3, COVID 19 Virus Disease, SARS Coronavirus 2 Infection, CD163v3, COVID 19, CD163v2COVID19, other disease, IPP2A2, dmBest1, Materials, mononuclear leukocyte, COVID-19, FBN, Virus Infection, Gene, SARS-CoV infection, COVID-19 Virus Diseases, 2019 novel coronavirus, CG30327, SARS ASSOC CORONAVIRUS, anon-WO0118547.380, Virus Disease, DmelCG6264, 2019 nCoV Disease, AI893580, PHAPII, 5730420M11Rik, CG11478, School-Age, SARS, diseases, ECTOL1, 2019-nCoV Disease, SARS CoV 2 Infection, Clinical Progression, Severe Acute Respiratory Syndrome Coronavirus 2 Infection, ARB, disease or disorder, diseases and disorders, β-coronavirus, 2019-nCoV, COVID 19 Pandemic, WMS, IFI-78K, CyTOF, Progression, study, School-Age Populations, DmelCG42257, SET, human disease, β-CoVs, Clinical, Genetic, TAF-I, SARS coronavirus infectious disease, VMD2, COVID-19 Virus Infection, ipp2a2, Coronavirus Disease 2019, 2pp2a, severe acute respiratory syndrome coronavirus 2, Coronavirus Disease-19, BMD, Population, SARS-CoV-2 Infection, beta-CoVs, 2010305L05Rik, ACEH, CG10574, Genotypes, OCTD, DmelCG4299, non-neoplastic, SARS coronavirus disease or disorder, COVID-19 Virus, IGAAD, set, Monocyte, 2PP2A, Clinical Course, DmelCG10574, taf-ibeta, Clients, 65K, UNQ868/PRO1885, CG42257, Dmel_CG30327, Exacerbation, dSET, dSet, disorder, Homo sapiens disease, snp, School Age Population, monocyte, GPHYSD2, COVID 19 Virus Disease, SARS Coronavirus 2 Infection, Respiratory Syndrome, nongranular leukocyte, SGS, 2019-nCoV Infections, RP50, phapii, Disease, cg11478, Coronavirus Disease 19, β-CoV, IFI78, CG6264, SARS coronavirus caused disease or disorder, beta-CoV, Mx-1, Disease Exacerbation, igaad, disorders, SARS-CoV-2, StF-IT-1, SARS-associated coronavirus, 2019 Novel Coronavirus Disease, SARS-CoV-2 Infections, 2019 nCoV Infection, COVID 19 Virus Infection, Cistrons, Client, results, group, ACMICD, COVID-19 Virus Disease, 2019-nCoV Infection, Genogroup, I-2PP2A, MX, School Age, CG6393, Dm I-2, I2PP2A, Diseases, Infection, Severe acute respiratory syndrome (disorder), Genetic Materials, condition, Coronavirus, MFS1, COVID-19 Virus Infections, TU15B, Genetic Material, WMS2, Severe Acute, dBest1, Dmel_CG6393, Populations, Dbest, mass cytometry assay, betacoronavirus, Disease 2019, HLA-DR-associated protein II, Pandemic, best, ensemble, DI-2, Mx, I-2Dm, severe acute respiratory syndrome, dbest1, MxA, MASS, CG4299, COVID-19 Pandemics, COVID-19 Pandemic, School Age Populations, SARS-coronavirus 2, I-2PP1, Genogroups, dSET/TAF-Ibeta, disease, 2610030F17Rik, Acute, TAF-IBETA, acute respiratory coronavirus infection, Patient, Material, SSKS, 2019 Novel Coronavirus Infection, Cistron, medical condition., TAF-Ibeta, 2019-nCoV Diseases, School-Age Population, AA407739, i2pp2a, BEST, COVID 19, SeverefalseRelevance of TMPRSS2, CD163/CD206 and CD33 in clinical severity stratification of COVID-19Our main objective is to incorporate new markers to classify COVID-19 patients based on mild or severe disease progression. To achieve this, we characterize SNP genotypes in critical genes involved in SARS-CoV infection (ACE2 (rs2285666), MX1 (rs469390), and TMPRSS2 (rs2070788) variants) and study the monocyte population by mass cytometry (CyTOF). Finally, the results obtained will be integrated to search for the best set of predictors of disease aggressiveness.2023-03-01 16:16:20EGAS000010070039606MONDO_0100096EGAD00010002445EGAC00001003090