{"database":"EGA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"study_type":["Cancer Genomics"],"full_dataset_link":["https://ega-archive.org/studies/EGAS00001007324"],"host":["EGA"],"description":["EGA study EGAS00001007324"],"dataset_title":["WGS and ONT Bams Accompanying Loose Ends Dataset"],"repository":["EGA"],"category":["restricted"],"name_synonyms":["primary cancer, Malignant Neoplasm, determination, Malignancy, Genomes, Neoplasms, Benign Neoplasm, conformation., Benign Neoplasms, Cancers, whole genome, Tumor, Malignant, malignant tumor, Malignant Neoplasms, Neoplasias, MT, Benign, malignant neoplasm, chemical analysis, Neoplasm, Malignancies, assay, Neoplasia, Cancer, Tumors"],"description_synonyms":["Forms, AU043015, X-linked, Malignant Neoplasm, KGFR, Neoplasms, mental retardation, Benign Neoplasm, number, Silver Russell syndrome, Silver Russell dwarfism, Tumor, Fgfr-7, Russell-Silver syndrome, Malignant, Fgfr-2, presence, Snyder type, inadequate, shortened, read, Readability, count in organism, Russell-Silver Syndrome, MT, Benign, X-linked mental retardation Snyder-Robinson type, MRXSSR, Neoplasm, Silver-Russell dwarfism, intellectual disability, Genomes., SPMSY, KGFRTr, primary cancer, Malignancy, Genomes, AW556123, Snyder-Robinson type, stubby, Benign Neoplasms, SRS, Srs, Cancers, whole genome, Understanding, Russell-Silver dwarfism, Russell Silver syndrome, malignant tumor, Malignant Neoplasms, MRSR, Fgfr7, Neoplasias, Bek, malignant neoplasm, X-linked intellectual disability, cardinality, svs, Malignancies, syndromic, SpS, Silver-Russell syndrome, short, X-linked intellectual disability Snyder-Robinson type, Neoplasia, Cancer, Tumors"],"additional_accession":[]},"is_claimable":false,"name":"Analysis of Loose Ends in Cancer Genome Structure","description":"Short-read sequencing (SRS) forms the basis of our understanding of cancer genome evolution, yet it is widely thought to be inadequate for detecting structural variants (SVs). To understand the nature of cancer SVs missed by SRS, we introduce the concept of \"loose ends\" - sites of missing rearrangements revealed by balancing copy number (CN) across the genomic intervals and adjacencies of a genome graph.","dates":{"updated":"2023-08-21 14:45:05"},"accession":"EGAS00001007324","cross_references":{"TAXONOMY":["9606"],"EGA":["EGAD00001011047","EGAC00001003290"]}}