EGAGenomicsRNASeqhttps://ega-archive.org/studies/EGAS00001007398EGAEGA study EGAS00001007398Total RNA sequencing data from the Triple Negative Trial (TNT)EGArestrictedANM, STNT, 5-trinitro-, 6-trinitrobenzene, Trotyl, 2-methyl-1, H, total RNA extract, Junk, Smack, 6-TNT, 1-methyl-2, 6-Trinitrotoluene, s-trinitrotoluene, cTnT, Tnt, TNT, NEM5, TNTS, alpha-TNT, Thunder, Trinitrotoluen, Black tar, Tritol, sym-Trinitrotoluol, 6-Trinitrotoluol., Trinitrotoluol, 2, s-Trinitrotoluol, 3, 4, trinitrotoluene, Benzene5-trinitro-, CG9490, CG13985, Forestland, Trotyl, MCK10, EDDR1, total RNA extract, Woodland., Smack, 6-TNT, 1-methyl-2, Forested Areas, cTnT, Tnt, TNT, CG13984, alpha-TNT, Trinitrotoluen, Black tar, HGK2, survival, Tritol, RTK6, DmelCG33531, Dmel_CG13984, CAK, Associations, responsivity, sym-Trinitrotoluol, OrR, Forested, Areas, 2, Area, s-Trinitrotoluol, 3, 4, trinitrotoluene, CT33540, ANM, STNT, reactivity, 6-trinitrobenzene, 2-methyl-1, Woodlands, H, death rate, Junk, 6-Trinitrotoluol, 6-Trinitrotoluene, DDR, s-trinitrotoluene, NEM5, free, TNTS, CG33531, Thunder, Forestlands, NTRK4, CG9488, PTK3, time of survival, Trinitrotoluol, Benzene, response, NEP, Forest, PTK3A, CG11573, CD167, TRKE, Forested AreafalseTotal RNA sequencing from the TNT trial (NCT00532727)Primary tumours from 186 TNT participants (13 matched recurrences) were profiled using total RNA-sequencing. Four transcriptional DDR-related and 25 immune-related signatures were evaluated. We assessed their association with objective-response-rate (ORR) and progression-free-survival (PFS) and performed conditional inference forest clustering to integrate multi-modal data.2023-07-21 15:11:04EGAS000010073989606EGAD00001011141EGAC00001003341