{"database":"EVA","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Vcf":["ftp://ftp.ebi.ac.uk/pub/databases/eva/PRJEB32049/PRJEB32049_merged.vcf.gz","ftp://ftp.ebi.ac.uk/pub/databases/eva/PRJEB32049/PRJEB32049_merged.accessioned.vcf.gz.tbi","ftp://ftp.ebi.ac.uk/pub/databases/eva/PRJEB32049/PRJEB32049_merged.vcf.gz.tbi","ftp://ftp.ebi.ac.uk/pub/databases/eva/PRJEB32049/PRJEB32049_merged.accessioned.vcf.gz"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":{"citationCount":0,"reanalysisCount":0,"viewCount":0,"searchCount":0},"additional":{"dataset_type":["Genotyping By Sequencing"],"omics_type":["Genomics"],"submitter":["University of Sao Paulo"],"instrument_platform":["-"],"species":["Bos Indicus"],"full_dataset_link":["https://www.ebi.ac.uk/eva/?eva-study=PRJEB32049"],"repository":["EVA"],"name_synonyms":["Taurine, dairy cow, Beef Cows, Materials, CG9057, cow, Taurus Cattles, Bos indicus Cattles, Holstein Cow, Taurus Cattle, Lsd2, Gene, Cattle, Taurine Cattles, LSD2, DmelCG9057, Indicine, Bos indicus, Dairy Cows, Cistrons, Domestic Cows., Bos grunniens, cattle, Bos taurus, Bos primigenius taurus, 145098_at, Genetic Materials, ADFP, domestic cattle, Indicine Cattles, Yaks, Holstein, Genetic Material, Cattles, ADRP, Yak, Genetic, Cows, Domestic Cow, Dairy Cow, Bos bovis, INSDC_feature:gene, LSD-2, Domestic, Dairy, Taurine Cattle, Beef, Bos Tauurus, Beef Cow, oxen, ox, Material, Cow, Taurus, plin2, Indicine Cattle, Cistron, Zebu, domestic cow, Zebus, Bos indicus Cattle, bovine"],"description_synonyms":["Saturated Fatty, Taurine, dairy cow, Esterified Fatty Acids, Materials, multi-cellular organism, CG9057, FESTA-L, FESTA-S, Spherosomes, selection process, Taurus Cattle, Lsd2, metazoans, Gene, LSD2, Lipid Bodies, protein, Dairy Cows, protein-containing complex, animals, Ximpact, Oleosomes, Mutations, Tier, sequestering of lipids, cattle, Roles, Associations, Gene Products, Concepts, Saturated Fatty Acids, AW048865, ADFP, Esterified Fatty Acid, Indicine Cattles, Animal, Lipid Storage Bodies, intramuscular triglycerides, protein aggregate, animal, U19, multicellular organismal biosynthetic process, Domestic Cows, Esterified, Animalia, imprinted and ancient gene protein, Yak, study, Fatty Acids, BM040, single-organism biosynthetic process, Muscle Tissues, Genetic, Cows, Tissues, Adiposome, Domestic Cow, long, Storage Bodies, Esterified Fatty, Dairy Cow, Aliphatic, Bos bovis, Tissue, metazoa, Domestic, LSD-2, Dairy, Taurine Cattle, Droplets, Beef, sequestration of lipid, genetic, Oil Bodies, Bos Tauurus, Aliphatic Acids, ch, Beef Cow, oxen, Oil Body, Cow, plin2, musculus, Role Concepts, site, Adiposomes, domestic cow, Zebus, constitutitional genetic, Spherosome, Saturated, Beef Cows, zebu, Lipid Droplet, lipid sequestering, cow, Taurus Cattles, Bos indicus Cattles, Lipid Body, Indicine cattle, protein complex, body, Traits, Holstein Cow, animalia, Proteins, familial, Oleosome, Cattle, Taurine Cattles, whole body, Indicine, DmelCG9057, Bos indicus, Muscle, Cistrons, impact-a, Programs, Concept, organism, Bos grunniens, Role Concept, native protein, Bos taurus, Bos primigenius taurus, Droplet, Lipid, Metazoa, zebu cattle, Protein, Role, lipid sequestration, sequence, Genetic Materials, 145098_at, IMPACT, imprinted and ancient gene protein homolog, domestic cattle, Bos taurus indicus, Yaks, Holstein, Genetic Material, Cattles, region, ADRP, Acid, Fatty Acid, Saturated Fatty Acid, whole organism, Programs., Aliphatic Acid, INSDC_feature:gene, muscle, TRAITS, Storage Body, primary structure of sequence macromolecule, muscle element, Protein Gene Products, multicellular animals, Gene Proteins, intramuscular fat, ox, Breedings, Material, Festa, Taurus, Koerper, Bos primigenius indicus, Lipid Storage Body, Indicine Cattle, Cistron, inherited genetic, Zebu, Bos indicus Cattle, bovine, E430016J11Rik, hereditary, Muscle Tissue, RWDD5"],"citation_count":["0"],"additional_accession":[]},"is_claimable":false,"name":"Identification of polymorphisms in the PLIN2 gene in Nellore cattle","description":"Genetic variations in genes involved in lipid storage may represent useful markers in marker assisted selection programs, which may interfere with important phenotypic traits such as intramuscular fat deposition in cattle. An important candidate gene is PLIN2 that plays a role in the capture of long chain fatty acids and in the formation and stabilization of lipid droplets in different tissues including muscle. The objective of this study was to identify and characterize polymorphisms present in the PLIN2 gene of Nellore animals. To date, there is not much information on mutations in the PLIN2 gene in Bos indicus animals. A total of 134 SNPs was identified in the genomic region of PLIN2 gene and five of those are novel with a moderate impact. These SNPs may change the protein effectiveness and, after further association studies and functional validation, could be used as genomic markers in animal breeding program.","dates":{"publication":"2019-04-23"},"accession":"PRJEB32049","cross_references":{"TAXONOMY":["9915"]}}