EVAapplication/xmlftp://ftp.ebi.ac.uk/pub/databases/eva/PRJEB32687/canine_variants.vcf.gzftp://ftp.ebi.ac.uk/pub/databases/eva/PRJEB32687/canine_variants.vcf.gz.tbiftp://ftp.ebi.ac.uk/pub/databases/eva/PRJEB32687/canine_variants.accessioned.vcf.gzprimaryOK200Genotyping By SequencingGenomicsPoznan University of Life Sciences, Poznan, Poland-Canis Lupus Familiarishttps://www.ebi.ac.uk/eva/?eva-study=PRJEB32687EVAAmbiguities, Disorders, Sex Differentiation, Intersex Conditions, Conditions, CARD, Sex., DSD, Hermaphroditism, Ambiguous, Sexual Development Disorder, Genitalia, sex differentiation disease, Differentiation Disorders, Sexual Differentiation, Sex Differentiation Disorder, Sexual, Disorders of Sexual Development, Genital, Ambiguity, Genital Ambiguity, differences of sex development, Sex Differentiation Disorders, sex differentiation disorder, Sex, Sexual Development Disorders, Sex Development Disorder, Intersexuality, conditions affecting reproductive development, disorders of sex development (DSD), Sexual Differentiation Disorder, disorders of sex development, disorder of sexual differentiation, Condition, Sexual Differentiation Disorders, Sex Development Disorders, sexual differentiation disorder, Pseudohermaphroditism, Differentiation Disorder, Disorder, Ambiguous Genitalia, Genital Ambiguities, Intersex, intersex conditions, Intersexualities, disorder of sex development, intersex, Intersex Condition, disorder of sex differentiationDNA (cytosine-5)-methyltransferase 1, Reproductive, atypia, GONAD, inborn, A930006B21Rik, aberrant, HSN1E, Canis familiaris, CARD, frequency, DNMT, metazoans, Genome Sequencing, connatal, DSD, Gonad, defective, dogs, MCMT, animals, 0710001O03Rik, Dog, Mutations, Subfertility, Aim, AIM, sex differentiation disease, Complete Genome, DNA methyltransferase HsaI, Metazoa, Canis canis, atypical, Infertility, Animal, outbreaks, Sanger sequencing, dog, Animalia, CXXC9, differences of sex development, Genotypic, DNMT1, ADCADN, Complete, sex differentiation disorder, Sex, Whole Genome, Genotypic Sex, UNQ203/PRO229, CT-2, DNMT1_HUMAN, occurrence, DNA (cytosine-5-)-methyltransferase 1, prevalence, Complete Genome Sequencing, disorders of sex development (DSD), conditions affecting reproductive development, disorders of sex development, disorder of sexual differentiation, surveillance, morbidity, CXXC-type zinc finger protein 9, Sub-Fertility, endemics, Sequencing, Phenotypic, multicellular animals, API6, AI317215, Canis domesticus, sexual differentiation disorder, sex, Breedings, Phenotypic Sex, infertility, Sterility, Reproductive Sterility, Whole, intersex conditions, Canis borealis, dye terminator sequencing., epidemics, disorder of sex development, Gonadal, Canis lupus borealis, intersex, gonad, disorder of sex differentiation, CXXC finger protein 9, CLEC2C, Gonads, incidence, m.HsaI, DNA MTase HsaIfalseA comprehensive characteristics of candidate genomic regions for canine monogenic disorders of sex developmentDisorders of sex development (DSD) are congenital conditions in which the chromosomal, gonadal or phentypical sex is atypical. The DSD are usually responsible for sterility or infertility and thus their occurrence in domestic animals is considered as an important breeding problem. The aim of the project is searching for the causative mutations in DSD dogs using whole genome sequencing, ddPCR and Sanger sequencing techniques.2020-01-02PRJEB326879615