{"database":"EVA","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Vcf":["ftp://ftp.ebi.ac.uk/pub/databases/eva/PRJEB33276/ribeiro2019.vcf.gz","ftp://ftp.ebi.ac.uk/pub/databases/eva/PRJEB33276/ribeiro2019.vcf.gz.tbi"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":{"citationCount":0,"reanalysisCount":0,"viewCount":0,"searchCount":0},"additional":{"dataset_type":["Genotyping By Array"],"omics_type":["Genomics"],"submitter":["Instituto de Ciencias e Innovacion en Medicina, Universidad del Desarrollo"],"instrument_platform":["-"],"species":["Homo Sapiens"],"full_dataset_link":["https://www.ebi.ac.uk/eva/?eva-study=PRJEB33276"],"repository":["EVA"],"name_synonyms":["genetic, Andes hantavirus, host organism, Infestation and Infection, wide, Andes virus, wide/broad, Genomes, Associations, Infection, familial, Infestations and Infections, study., inherited genetic, Infection and Infestation, Infections and Infestations, whole genome, broad, constitutitional genetic, hereditary, clinical infection"],"description_synonyms":["cluster, host organism, Andes Virus, human being, Dobrava-Belgrade Virus, wide/broad, syndrome associated with disease or disorder, Modern, familial, number, Goal, Clusters, broad, syndromic disease or disorder, presence, Client, Associations., Andes Hantavirus, Human, Dobrava Belgrade Virus, count in organism, symptom cluster, Andes virus, \"syndrome, Homo sapiens, Symptom Cluster, \"syndrome\" EXACT [MTH:NOCODE], symptom clusters, symptom, Orthohantaviruses, Man, Andes hantavirus, Hantaviruses, Andes Hantaviruses, Man (Taxonomy), four corners hantavirus, Genomes, syndrome, whole genome, syndromes, human, HARDS, Symptom, clusters, genetic, Andes, wide, NOS\" EXACT [SNOMEDCT_2005_07_31:64572001], Syndromes, Cluster, Patient, syndromic disease, Clients, Modern Man, Symptom Clusters, cardinality, inherited genetic, constitutitional genetic, hereditary, Hantavirus, Hantavirus-associated respiratory distress syndrome, Severe"],"citation_count":["0"],"additional_accession":[]},"is_claimable":false,"name":"Host genetic factors and severity of Andes orthohantavirus infection: a genome wide association study","description":"Andes orthohantavirus (ANDV) is an important human pathogen that cause hantavirus cardiopulmonary syndrome (HCPS) with a fatality rate of 30% in Chile. Clinical course may present as a mild or severe illness. The influence of genetic factors of the host in the different clinical courses is currently poorly understood. Our goal was to identify copy number variats (CNVs) associated with different clinical courses (mild or severe) in patients infected with ANDV. We recruited 195 patients (88 mild and 107 severe). Genotyping was performed using Affymetrix Genome-Wide SNP Array 6.0. We performed CNVs Genome Wide Association (GWAs) analisys.","dates":{"publication":"2019-07-04"},"accession":"PRJEB33276","cross_references":{"TAXONOMY":["9606"]}}