{"database":"EVA","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Vcf":["ftp://ftp.ebi.ac.uk/pub/databases/eva/PRJEB94535/AncestryMarkers_255samples_LDPruned.vcf.gz","ftp://ftp.ebi.ac.uk/pub/databases/eva/PRJEB94535/epic_germline_b2_99_AC_AF.vcf.gz.csi","ftp://ftp.ebi.ac.uk/pub/databases/eva/PRJEB94535/epic_germline_b2_99_AC_AF.vcf.gz","ftp://ftp.ebi.ac.uk/pub/databases/eva/PRJEB94535/AncestryMarkers_255samples_LDPruned.vcf.gz.csi"],"Other":["ftp://ftp.ebi.ac.uk/pub/databases/eva/PRJEB94535/epic_germline_b2_99_AC_AF.vcf.csi","ftp://ftp.ebi.ac.uk/pub/databases/eva/PRJEB94535/AncestryMarkers_255samples_LDPruned.vcf.csi"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"dataset_type":["Whole Genome Sequencing"],"omics_type":["Genomics"],"submitter":["The University of Sydney"],"instrument_platform":["-"],"species":["Homo Sapiens"],"full_dataset_link":["https://www.ebi.ac.uk/eva/?eva-study=PRJEB94535"],"repository":["EVA"],"additional_accession":[]},"is_claimable":false,"name":"Development of a southern African-relevant methylome-wide EPIC filtering resource for SNP-confounded probe removal","description":"A southern African-relevant variant filtering resource was generated using high-coverage (mean 43X) whole genome sequencing data from 99 genetically confirmed southern African individuals. Germline single nucleotide variants (SNVs) and small insertions/deletions (<50 bp) were called against the GRCh38 reference genome, and variants with a minor allele frequency (MAF) >0.01 were retained to create a population-specific filter optimised for downstream genomic analyses in southern African cohorts. Ancestry markers used to determine the ancestry of these 99 individuals and an additional 192 individuals are included.","dates":{"publication":"2025-08-12"},"accession":"PRJEB94535","cross_references":{"TAXONOMY":["9606"]}}