GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE100nnn/GSE100473/primaryOK2000000GenomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE100473GEOGSE0falseEffect of O-GlcNAc transferase deficiency on intestinal epithelial cells in miceO-GlcNAcylation is the modification of serine and threonine residues with beta-N-acetylglucosamine (O-GlcNAc) on intracellular proteins. To investigate the role of protein O-GlcNAcylation on intestinal homeostasis, we generated intestinal epithelial cell (IEC)-specific O-GlcNAc transferase (OGT) knockout in mice. The KO mice developed spontanous intestinal inflammation. To determine the underlying molecular mechanisms, we performed RNA sequencing of ileum and colon epithelial cells of wildtype and IEC-OGT KO mice.2017/06/27GSE100473GSM2684730GSM2684723GSM2684722GSM2684721GSM2684720GSM2684727GSM2684726GSM2684725GSM2684724GSM2684729GSM268472817021SRP110508100473Mus musculus[29941542]