{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE103nnn/GSE103454/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by array"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE103454"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"mRNA expression data from overexpression or inhibition of miR-340 in 451 Lu melanoma cells","description":"Characterizing miRNA function remains challenging due to an abundance of predicted targets and an experimental bottleneck in identifying biologically relevant direct targets. We developed a novel technique (miFAST) to identify direct miRNA target genes. Using miFAST, we confirmed several previously reported miR-340 target genes and identified five additional novel direct miR-340 targets in melanoma cells. This methodology can also be efficiently applied for the global characterization of miRNA targets.","dates":{"publication":"2017/09/06"},"accession":"GSE103454","cross_references":{"GSM":["GSM2771669","GSM2771658","GSM2771668","GSM2771657","GSM2771659","GSM2771672","GSM2771661","GSM2771660","GSM2771671","GSM2771663","GSM2771662","GSM2771665","GSM2771664","GSM2771667","GSM2771656","GSM2771666","GSM2771655","GSM2771670"],"GPL":["16686"],"GSE":["103454"],"taxon":["Homo sapiens"],"PMID":["[29350431]"]}}