GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE106nnn/GSE106278/primaryOK200TranscriptomicsCandida albicans Genome binding/occupancy profiling by genome tiling arrayExpression profiling by arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE106278GEOGSEfalseThe genomic landscape of the fungal specific SWI/SNF complex subunit, Snf6, in Candida albicansWe have focused our investigation on the characterization of the role of the fungal specific SWI/SNF subunit, Snf6. Our data show that, although the C. albicans subunit has only limited sequence similarity to other fungal orthologs, Snf6 was copurified with SWI/SNF complex subunits including the catalytic ATPase subunit, Snf2. We show that Snf6 plays a critical role in biological processes that are essential for fungal pathogenesis including carbon metabolic flexibility, stress response and morphogenesis. The Snf6 regulon was determined by combining both genome-wide location (ChIP-chip) and transcriptional profiling (microarrays) to identify targets of the SWI/SNF complex under both yeast- and hyphal-promoting conditions.2017/10/28GSE106278GSM2834529GSM2834527GSM2834528GSM2834877GSM2834526GSM2834875GSM2834876GSM2834874GSM2834530106369818106278Candida albicans[29152582]