GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE113nnn/GSE113796/primaryOK2000000GenomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE113796GEOGSE0falsemRNA-Seq of mouse Mettl3 cKO and Fto cKO hippocampus after fear conditioningN6-Methyladenosine (m6A) and N6,2′-O-dimethyladenosine (m6Am) are abundant mRNA modifications that regulate transcript processing and translation. The role of both, here termed m6A/m, in the stress response in the adult brain in vivo are currently unknown. Here, we investigated the effect of gene deletion of Mettl3, a m6A methyltransferase, and Fto, a m6A and m6Am demethlyase, induced in adulthood in excitatory neurons of the CA1 and CA3 in the hippocampus (Nex-CreERT2 Mettl3 or Fto cKO) on the transcriptome of CA1 and CA3 as well as the transcriptomic response of the CA1 and CA3 transcriptome to fear conditioning.2018/07/10GSE113796GSM3119558GSM3119536GSM3119557GSM3119535GSM3119538GSM3119537GSM3119539GSM3119519GSM3119550GSM3119552GSM3119530GSM3119551GSM3119554GSM3119532GSM3119531GSM3119553GSM3119534GSM3119556GSM3119555GSM3119533GSM3119525GSM3119547GSM3119546GSM3119524GSM3119549GSM3119527GSM3119548GSM3119526GSM3119529GSM3119528GSM3119541GSM3119540GSM3119543GSM3119521GSM3119520GSM3119542GSM3119523GSM3119545GSM3119544GSM311952221103SRP143686113796Mus musculus[30048615]