GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE119nnn/GSE119650/primaryOK2000000GenomicsMus musculusExpression profiling by arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE119650GEOGSE0falseTranscriptomes of microglia in experimental cerebral malaria in mice in the presence and absence of Type I Interferon signalingPlasmodium berghei ANKA infection in mice is used as a model for human cerebral malaria, the most severe complication of Plasmodium falciparum infection. The response of brain cells such as microglia has been little investigated, and may play a role in the pathogenesis or regulation of cerebral malaria. We showed previously that microglia are activated in P. berghei infections, and that Type 1 Interferon signaling is important for activation. This dataset contains the transcriptome of brain microglia of infected mice in the presence and absence of Type I interferon signaling, with the aim of identifying the genes involved in this pathway in microglia during experimental cerebral malaria. Refererence: Capuccini et al 2016, Scientific Reports, 6:39258 The global gene expression profiles from RNA of microglia isolated from uninfected and P berghei-infected wild-type C57BL/6 mice and and IFNA Receptor Knock-out mice using Illumina Beadarrays.2018/09/07GSE119650GSM3380255GSM3380266GSM3380265GSM3380254GSM3380268GSM3380257GSM3380256GSM3380267GSM3380259GSM3380269GSM3380258GSM3380271GSM3380260GSM3380270GSM3380251GSM3380262GSM3380261GSM3380272GSM3380264GSM3380253GSM3380263GSM33802526887119650Mus musculus[27991544][30670056][30572937]