GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE128nnn/GSE128032/primaryOK200Methylation profilingHomo sapiensMethylation profiling by genome tiling arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE128032GEOGSEfalseLoss of IDH1R132H mediated D-2HG production induces genome-wide demethylation in GCIMP low loci in patient-derived glioma cellsHere, we describe and characterize CRISPR-Cas9 based isogenic cell line models using patient-derived IDH1R132H/WT glioma cell lines, and we use these models to explore changes in DNA methylation following genetic deletion of IDH1 alleles that ablate D2HG production.2019/11/07GSE128032GSM3660636GSM3660625GSM3660635GSM3660634GSM3660633GSM3660629GSM3660639GSM3660628GSM3660627GSM3660638GSM3660626GSM3660637GSM3660632GSM3660631GSM3660630GSM366064021145128032Homo sapiens[31292202]