GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE139nnn/GSE139292/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE139292GEOGSEfalseComparison of different shear stress conditions on gene proflile modulation in HCASMC and HCAEC, in the presence or absence of BVS+EverolimusWe have analyzed the global gene expression modulation induced by mechanical stress (shear stress) on vascular wall cells, seeded in the Ibidi system, with and without BVS+Drug. By the comparison of the different flow conditions we obtained a small panel of genes, mainly involved in inflammation, angiogenesis, leukocyte migration, smooth muscle cell growth, thrombosis (BMP4, SELE, HMOX1, MEOX2, SEMA3E): all these genes will be integrated in an in-silico model for the evaluation of restenosis and thrombosis development after BVS deployment. This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 7771192020/11/01GSE139292GSM4136344GSM4136345GSM4136323GSM4136342GSM4136320GSM4136321GSM4136348GSM4136326GSM4136349GSM4136327GSM4136324GSM4136346GSM4136328GSM4136329GSM4136362GSM4136340GSM4136341GSM4136363GSM4136360GSM4136333GSM4136356GSM4136353GSM4136331GSM4136332GSM4136354GSM4136359GSM4136337GSM4136338GSM4136316GSM4136335GSM4136357GSM4136336GSM4136319GSM4136317GSM4136352GSM413635018573SRP227120139292Homo sapiens