{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE143nnn/GSE143826/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE143826"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptome changes in BMDM cells of Trex1 knockout mouse before and after STING antagonists treatments","description":"Trex1 is known as a major cellular 3'-to-5' exonuclease which could digest both single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini. Loss of Trex1 led to cell-intrinsic initiation of autoimmunity. Here, we investigated transcriptome changes in BMDM cells of Trex1 knockout mouse after STING antagonists (SN-011, H151) treatments.","dates":{"publication":"2026/05/15"},"accession":"GSE143826","cross_references":{"GSM":["GSM4275095","GSM4275100","GSM6304212","GSM4275099","GSM4275098","GSM6304211","GSM4275097","GSM4275096"],"GPL":["17021"],"SRA":["SRP242310"],"GSE":["143826"],"taxon":["Mus musculus"],"PMID":["[41773721]"]}}