GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE158nnn/GSE158800/primaryOK200GenomicsMus musculusGenome binding/occupancy profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE158800GEOGSEfalseGenetically defined syngeneic mouse models of ovarian cancer as tools for the discovery of combination immunotherapy (ATAC-seq)Purpose: There are three goals of this study: 1. To compare the genomic, exome and chromatin accessiblity profiles of the specific engineered fallopian tube cells of high-grade serous tubo-ovarian cancer (HGSC) models (this study) using whole-exome, whole-genome and ATAC-seq sequencing. Methods: Cells were harvested and frozen in culture media containing FBS and 5% DMSO. Cryopreserved cells were sent to Active Motif (Carlsbad, CA) to perform the ATAC-seq assay. Conclusions: We conclude that whole-exome, whole-genome and ATAC-seq characterization would expedite genetic network analyses and permit the dissection of complex biological functions.2026/09/14GSE158800GSM4810579GSM4810580GSM481058119057SRP285891158800Mus musculus