GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE164nnn/GSE164138/primaryOK200OtherHomo sapiensOtherhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE164138GEOGSEfalseSequencing 5-formyluracil in genome DNA at single-base resolutionAlbeit with low content, in genome DNA, the 5-formyluracil has been an important modification. The 5-formyluracil was found to be widely distributed amongst living bodies (prokaryotes and mammalian cells). Capable of binding to proteins to prevent the gene expressions, the 5-formyluracil could also induce mismatch in the DNA. In certain cancerous tissues, the content of 5-formyluracil was found to be higher than the normal tissues adjacent to the tumor. Nonetheless, the lack of a higher resolution mapping technique, has been hampering the studies of 5-formyluracil. Hence, we adopted the single-base resolution analysis method to profile 5-formyluracil at the genome scale. We analyzed the distribution of 5-formyluracil in the genome. This technique enabled us to have a better understanding of 5-formyluracil.2022/12/01GSE164138GSM4998043GSM4998044GSM4998041GSM4998042GSM4998040GSM499803920795SRP300041164138Homo sapiens