GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE16nnn/GSE16475/primaryOK2000000GenomicsMus musculusExpression profiling by arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE16475GEOGSE0falseExpression data from side population subfraction hematopoietic stem cellsThe traditional view of hematopoiesis has been that all the cells of the peripheral blood are the progeny of a unitary homogeneous pool of hematopoietic stem cells (HSCs). Recent evidence suggests that the hematopoietic system is actually maintained by a consortium of HSC subtypes with distinct functional characteristics. We show here that myeloid-biased HSCs (My-HSCs) and lymphoid-biased (Ly-HSCs) can be purified according to their capacity for Hoechst dye efflux in combination with canonical HSC markers. We used microarray expression profiling to determine the transcriptional profiles of myeloid-biased lower-SP HSCs and lymphoid-biased upper-SP HSCs2010/03/01GSE16475GSM413997GSM413998GSM413995GSM413996GSM413999GSM413994126116475Mus musculus[20207229]