{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE168nnn/GSE168638/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":[" Schizosaccharomyces pombe","Saccharomyces cerevisiae"],"gds_type":["Expression profiling by array"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE168638"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Expression data from budding yeast sec12-4 and sec12-4 ino2Δino4Δ mutant cells","description":"Sec12 is a guanine nucleotide exchange factor (GEF) required for the initiation of COPII vesicle formation in ER to Golgi transport. The sec12-4 mutant cells show temperature sensitivity in growth and a defect in ER-to-Golgi protein transport. Ino2/Ino4 are components of the heteromeric basic helix-loop-helix transcription activator that binds inositol/choline-responsive elements (ICREs) and are required for derepression of phospholipid biosynthetic genes in response to inositol depletion. We used microarrays to compare the global gene expression profiles between sec12-4 and sec12-4 ino2Δino4Δmutant cells.","dates":{"publication":"2026/04/01"},"accession":"GSE168638","cross_references":{"GSM":["GSM5151936","GSM5151939","GSM5151937","GSM5151938","GSM5151940","GSM5151941"],"GPL":["2529"],"GSE":["168638"],"taxon":[" Schizosaccharomyces pombe","Saccharomyces cerevisiae"]}}