GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE17nnn/GSE17661/primaryOK2000000GenomicsRattus norvegicusExpression profiling by arrayhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE17661GEOGSE0falseModulation of gene expression by rapamycin in hepatic cell lines, WB-F344 and WB311Two rat hepatic cell lines, WB-F344 and WB311, were characterized for the effect of rapamycin on gene expression. The WB311 cell line, which is tumorigenic and resistant to the growth inhibitory effects of rapamycin, was originally derived from the WB-F344 parental hepatic epithelial cell line. The goal of this experiment was to identify genes that responded to rapamycin in the sensitive cells but not the resistant cells, thereby providing insight into the mechanism of rapamycin resistance.2009/09/20GSE17661GSM440879GSM440889GSM440888GSM440887GSM440882GSM440881GSM440880GSM440890GSM440886GSM440885GSM440884GSM440883135517661Rattus norvegicus[19816606]