GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE178nnn/GSE178562/primaryOK200TranscriptomicsMus musculus Homo sapiens Genome binding/occupancy profiling by high throughput sequencingExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE178562GEOGSEfalseJUN promotes hypertrophic skin scarring via CD36Hypertrophic skin scarring following dermal injury causes extreme pain and psychological trauma for patients. Unfortuately, we do not have effective treatments to prevent or reverse skin scarring. Using RNA and ATAC sequencing of mouse and human fibroblasts, we show that JUN expressing fibroblasts are responsible for skin scarring by regulating CD36 expression. In summary, we show that CD36 antagonism by represent a therapeutic target to overcome JUN hypertrophic skin scarring.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 musculus Homo sapiens[34516825]