{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE192nnn/GSE192686/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Candida albicans"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE192686"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Candida albicans adapts to toxic levels of the quorum sensing molecule farnesol through cell wall remodeling","description":"In this study, we discover that Candida albicans tolerates farnesol by actively remodeling its cell wall to generate a thicker, less permeable cell wall. Using RNA seq, we found that C. albicans cells respond to exogenous farnesol by mounting a stress response that involves the upregulation of genes involved in drug efflux, protein folding, redox homeostasis,and cell wall assembly.","dates":{"publication":"2026/07/21"},"accession":"GSE192686","cross_references":{"GSM":["GSM5755697","GSM5755696","GSM5755699","GSM5755698","GSM5755701","GSM5755700","GSM5755702","GSM5755695"],"GPL":["24129"],"GSE":["192686"],"taxon":["Candida albicans"]}}