{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE198nnn/GSE198499/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE198499"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Phf6 mutation induces leukemogenesis through altered chromatin state in mice (RNA-Seq)","description":"To investigate the effect of PHF6 mutations in leukemogenesis, we generated Phf6R274X transgenetic(Tg) and Phf6 KO mice. Then we purified the Lineage-cKit+Sca-1+ cells from bone marrow of Phf6R274XTg, Phf6 KO and WT mice, and performed bulk RNA-seq to profile the transcriptom.","dates":{"publication":"2026/06/01"},"accession":"GSE198499","cross_references":{"GSM":["GSM5949624","GSM5949625","GSM5949633","GSM5949623","GSM5949631","GSM5949632","GSM5949630","GSM5949628","GSM5949629","GSM5949626","GSM5949627"],"GPL":["19057"],"GSE":["198499"],"taxon":["Mus musculus"]}}