GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE198nnn/GSE198499/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE198499GEOGSEfalsePhf6 mutation induces leukemogenesis through altered chromatin state in mice (RNA-Seq)To investigate the effect of PHF6 mutations in leukemogenesis, we generated Phf6R274X transgenetic(Tg) and Phf6 KO mice. Then we purified the Lineage-cKit+Sca-1+ cells from bone marrow of Phf6R274XTg, Phf6 KO and WT mice, and performed bulk RNA-seq to profile the transcriptom.2026/06/01GSE198499GSM5949624GSM5949625GSM5949633GSM5949623GSM5949631GSM5949632GSM5949630GSM5949628GSM5949629GSM5949626GSM594962719057198499Mus musculus