{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE198nnn/GSE198501/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE198501"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Phf6 mutation induces leukemogenesis through altered chromatin state in mice (scRNA-Seq)","description":"To investigate the effect of PHF6 mutations in leukemogenesis, we generated Phf6R274X transgenetic(Tg) mice. Then we purified the Lineage-cKit+ cells from bone marrow of Phf6R274XTg and WT mice, and performed single cell RNA-seq to study hematopoietic stem cell differentiation trajectory.","dates":{"publication":"2026/06/01"},"accession":"GSE198501","cross_references":{"GSM":["GSM5949646","GSM5949647","GSM5949648","GSM5949649"],"GPL":["21493"],"GSE":["198501"],"taxon":["Mus musculus"]}}