GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE199nnn/GSE199064/primaryOK200TranscriptomicsMus musculus Genome binding/occupancy profiling by high throughput sequencingExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE199064GEOGSEfalseSingle cell multiomic landscape reveals gene programs driving lipid droplet heterogeneity in hepatic steatosisAlcohol-associated liver disease (ALD) in its earliest form is evidenced as hepatic steatosis which may progress to liver cirrhosis. Using single-cell multiomics technology, we studied transcriptional mechanisms across the hepatic lobule that could account for liver zonation of lipid droplets in a murine ALD model. Furthermore, chromatin landscape studies demonstrated zonation of regulatory elements and master transcription factors associated with these changes in the transcriptome.2026/04/01GSE199064GSM5963648GSM5963649GSM5963650GSM596365121103199064Mus musculus[41730984]