GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE210nnn/GSE210051/primaryOK200Genomicssynthetic construct Mus musculusOtherhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE210051GEOGSEfalseDNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and in response to immunotherapy [DNA barcodes: IT_and_cont_4T1_BC250000]To investigate immunoediting at the primary tumour, we used DNA barcoding combined with NGS. By stably integrating 4T1 murine cancer cell line with 250000 unique DNA barcodes (1 barcode per cell), we can trace how barcode (and therefore subclonal) diversity changes over time and after treatment with immunotherapy.2022/08/02GSE210051GSM6415870GSM6415871GSM6415872GSM6415850GSM6415873GSM6415851GSM6415852GSM6415874GSM6415875GSM6415853GSM6415876GSM6415854GSM6415855GSM6415877GSM6415878GSM6415856GSM6415879GSM6415857GSM6415858GSM6415859GSM6415880GSM6415881GSM6415882GSM6415860GSM6415861GSM6415862GSM6415863GSM6415864GSM6415865GSM6415866GSM6415867GSM6415868GSM6415869GSM64158491942419057210051synthetic construct Mus musculus[36344500]