GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE224nnn/GSE224414/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE224414GEOGSEfalseEffect of depletion of SPAST exon17 on gene expression in human embryonic stem cells (hESC) and cortical organoids (COs)To investigate neurodegenerative disease, we established SPAST exon17 knock-out in hESCs in which target gen have been knocked down by CRISPR/Cas9, differentiated into COs.2026/04/06GSE224414GSM7021910GSM7021909GSM7021908GSM7021907GSM7021906GSM7021916GSM7021905GSM7021915GSM7021914GSM7021913GSM7021912GSM702191116791224414Homo sapiens