<HashMap><database>GEO</database><file_versions><headers><Content-Type>application/xml</Content-Type></headers><body><files><Other>ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE225nnn/GSE225862/</Other></files><type>primary</type></body><statusCode>OK</statusCode><statusCodeValue>200</statusCodeValue></file_versions><scores/><additional><omics_type>Genomics</omics_type><species>Mus musculus</species><gds_type>Non-coding RNA profiling by high throughput sequencing</gds_type><full_dataset_link>https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE225862</full_dataset_link><repository>GEO</repository><entry_type>GSE</entry_type></additional><is_claimable>false</is_claimable><name>Endothelin-1 overexpression in mice increases vascular Vegfa164 and Vegfa188 alternative splice isoforms via enhanced Khdrbs3 expression</name><description>Transgenic mice with tamoxifen-inducible endothelium-restricted human endothelin-1 overexpression (ieET-1) exhibited blood pressure (BP) elevation after 3 weeks and 3 months induction. Vascular injury was observed only after a 3-month exposure to human ET-1 overexpression. It is unknown whether 3-week or 3-month exposure to ET-1 overexpression results in gene dysregulation. We aimed to identify differentially expressed (DE) microRNAs and total RNA in mesenteric arteries of ieET-1 mice after 3-week and 3-month induction of human ET-1 overexpression.</description><dates><publication>2026/05/15</publication></dates><accession>GSE225862</accession><cross_references><GSM>GSM7058839</GSM><GSM>GSM7058838</GSM><GSM>GSM7058846</GSM><GSM>GSM7058845</GSM><GSM>GSM7058848</GSM><GSM>GSM7058847</GSM><GSM>GSM7058842</GSM><GSM>GSM7058841</GSM><GSM>GSM7058863</GSM><GSM>GSM7058844</GSM><GSM>GSM7058843</GSM><GSM>GSM7058860</GSM><GSM>GSM7058862</GSM><GSM>GSM7058840</GSM><GSM>GSM7058861</GSM><GSM>GSM7058849</GSM><GSM>GSM7058835</GSM><GSM>GSM7058857</GSM><GSM>GSM7058856</GSM><GSM>GSM7058834</GSM><GSM>GSM7058859</GSM><GSM>GSM7058837</GSM><GSM>GSM7058858</GSM><GSM>GSM7058836</GSM><GSM>GSM7058853</GSM><GSM>GSM7058852</GSM><GSM>GSM7058855</GSM><GSM>GSM7058833</GSM><GSM>GSM7058832</GSM><GSM>GSM7058854</GSM><GSM>GSM7058851</GSM><GSM>GSM7058850</GSM><GPL>17021</GPL><GSE>225862</GSE><taxon>Mus musculus</taxon><PMID>[42253124]</PMID></cross_references></HashMap>