GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE225nnn/GSE225866/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE225866GEOGSEfalseEndothelin-1 overexpression in mice increases vascular Vegfa164 and Vegfa188 alternative splice isoforms via enhanced Khdrbs3 expressionTransgenic mice with tamoxifen-inducible endothelium-restricted human endothelin-1 overexpression (ieET-1) exhibited blood pressure (BP) elevation after 3 weeks and 3 months induction. Vascular injury was observed only after a 3-month exposure to human ET-1 overexpression. It is unknown whether 3-week or 3-month exposure to ET-1 overexpression results in gene dysregulation. We aimed to identify differentially expressed (DE) microRNAs and total RNA in mesenteric arteries of ieET-1 mice after 3-week and 3-month induction of human ET-1 overexpression.2026/05/15GSE225866GSM7058908GSM7058905GSM7058904GSM7058907GSM7058906GSM7058901GSM7058900GSM7058889GSM7058903GSM7058902GSM7058897GSM7058886GSM7058885GSM7058896GSM7058888GSM7058899GSM7058898GSM7058887GSM7058893GSM7058892GSM7058895GSM7058894GSM7058891GSM705889017021225866Mus musculus