{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE233nnn/GSE233383/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":[" Mus musculus","Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE233383"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Gene expression and splicing profiles across models of TTDN1 deficiency","description":"The molecular networks disrupted in Non-photosensitive trichothiodystrophy (NP-TTD) are largely uncharacterized. NP-TTD is linked to mutations in the gene encoding TTDN1, an uncharacterized protein thought to have functions in splicing or trasncription . The goals of this study are to identify splicing and gene expression defects occuring in multiple models of TTDN1 deficiency, including U2OS and Hela-S cell lines, as well as in cortical tissue from TTDN1 deficient mice.","dates":{"publication":"2023/09/13"},"accession":"GSE233383","cross_references":{"GSM":["GSM7426656","GSM7426634","GSM7426655","GSM7426633","GSM7426658","GSM7426636","GSM7426635","GSM7426657","GSM7426630","GSM7426652","GSM7426673","GSM7426651","GSM7426654","GSM7426632","GSM7426653","GSM7426631","GSM7426638","GSM7426637","GSM7426659","GSM7426639","GSM7426670","GSM7426650","GSM7426672","GSM7426671","GSM7426667","GSM7426645","GSM7426644","GSM7426666","GSM7426647","GSM7426669","GSM7426668","GSM7426646","GSM7426641","GSM7426663","GSM7426640","GSM7426662","GSM7426665","GSM7426643","GSM7426664","GSM7426642","GSM7426627","GSM7426649","GSM7426648","GSM7426626","GSM7426629","GSM7426628","GSM7426661","GSM7426660"],"GPL":["24676","24247"],"GSE":["233383"],"taxon":[" Mus musculus","Homo sapiens"],"PMID":["[37369199]"]}}