GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE233nnn/GSE233383/primaryOK200Transcriptomics Mus musculusHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE233383GEOGSEfalseGene expression and splicing profiles across models of TTDN1 deficiencyThe molecular networks disrupted in Non-photosensitive trichothiodystrophy (NP-TTD) are largely uncharacterized. NP-TTD is linked to mutations in the gene encoding TTDN1, an uncharacterized protein thought to have functions in splicing or trasncription . The goals of this study are to identify splicing and gene expression defects occuring in multiple models of TTDN1 deficiency, including U2OS and Hela-S cell lines, as well as in cortical tissue from TTDN1 deficient mice.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 Mus musculusHomo sapiens[37369199]