{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE233nnn/GSE233624/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE233624"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Single cell transcriptome atlas revealed the feature of contemporary ZIKA virus induced microcephaly in mice","description":"Zika virus (ZIKV), a mosquito-borne flavivirus, has imposed tremendous global threat to human health and was declared as a public health emergency of international concern by the World Health Organization in 2016. However, the pathogenic mechanism of ZIKV still lacks sufficient understanding. In recent years, the development of single-cell sequencing technology has provided a more precise approach for exploring disease mechanisms. Therefore, in this study, we depicted a high-resolution transcriptomic landscape and functional changes of brain immune and neural cells during disease progression of ZIKV, which will facilitate a better understanding of the underlying pathogenesis of ZIKV-induced microcephaly.","dates":{"publication":"2026/06/01"},"accession":"GSE233624","cross_references":{"GSM":["GSM7431636","GSM7431635","GSM7431637"],"GPL":["24247"],"GSE":["233624"],"taxon":["Mus musculus"]}}