GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE233nnn/GSE233699/primaryOK200OtherHomo sapiensOtherhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE233699GEOGSEfalseRibo-seq from cells with depletion of DIS3 from human cell linesDIS3 is a 3’ to 5’ exoribonuclease responsible for degradation of multiple RNA targets. Most reports in human cells focus on its function in RNA surveillance in the nucleus. However, a small fraction of DIS3 can be also found in cytoplasm. Thus, the focus of this experiment was to identify the cytoplasmic targets of DIS3 that can be translated. Using rapid, auxin inducible, degradation of DIS3 protein and ribosome profiling, we were able to identify RNA accumulated in cytoplasm containing non-canonical Open Reading Frames . The raw data and counts for from the experiment are provided.2026/06/02GSE233699GSM7432739GSM7432741GSM7432740GSM7432734GSM7432736GSM7432735GSM7432738GSM743273724676233699Homo sapiens