{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE233nnn/GSE233722/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE233722"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Effect of RNF4 depletion on GSK3685032-induced gene expression changes in MV4-11 cells [RNA-seq]","description":"GSK3685032-induced DNA hypomethylation results in upregulation of largely viral-responsive gene expression pathways and cell death. We identified that loss of RNF4 causes resistance to GSK3685032. We established RNF4 wild type and deficient MV4-11 cells by CRISPR-Cas9 disruption and treated with vehicle or GSK3685032 to determine how RNF4-deficiency impacts GSK3685032-induced gene expression changes","dates":{"publication":"2026/05/17"},"accession":"GSE233722","cross_references":{"GSM":["GSM7433253","GSM7433254","GSM7433251","GSM7433252","GSM7433257","GSM7433247","GSM7433258","GSM7433255","GSM7433256","GSM7433248","GSM7433249","GSM7433250"],"GPL":["24676"],"GSE":["233722"],"taxon":["Homo sapiens"]}}