{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE233nnn/GSE233727/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Methylation profiling"],"species":["Homo sapiens"],"gds_type":["Methylation profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE233727"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Effect of RNF4 depletion on GSK3685032-induced gene expression changes in MV4-11 cells [RRBS]","description":"GSK3685032-induced DNA hypomethylation results in upregulation of largely viral-responsive gene expression pathways and cell death. We identified that loss of RNF4 causes resistance to GSK3685032. We established RNF4 wild type and deficient MV4-11 cells by CRISPR-Cas9 disruption and treated with vehicle or GSK3685032 to determine how RNF4-deficiency impacts GSK3685032-induced gene expression changes","dates":{"publication":"2026/05/17"},"accession":"GSE233727","cross_references":{"GSM":["GSM7433294","GSM7433297","GSM7433298","GSM7433295","GSM7433296","GSM7433312","GSM7433301","GSM7433313","GSM7433302","GSM7433310","GSM7433299","GSM7433311","GSM7433300","GSM7433305","GSM7433306","GSM7433303","GSM7433304","GSM7433309","GSM7433307","GSM7433308"],"GPL":["24676"],"GSE":["233727"],"taxon":["Homo sapiens"]}}