GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE233nnn/GSE233727/primaryOK200Methylation profilingHomo sapiensMethylation profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE233727GEOGSEfalseEffect of RNF4 depletion on GSK3685032-induced gene expression changes in MV4-11 cells [RRBS]GSK3685032-induced DNA hypomethylation results in upregulation of largely viral-responsive gene expression pathways and cell death. We identified that loss of RNF4 causes resistance to GSK3685032. We established RNF4 wild type and deficient MV4-11 cells by CRISPR-Cas9 disruption and treated with vehicle or GSK3685032 to determine how RNF4-deficiency impacts GSK3685032-induced gene expression changes2026/05/17GSE233727GSM7433294GSM7433297GSM7433298GSM7433295GSM7433296GSM7433301GSM7433312GSM7433313GSM7433302GSM7433310GSM7433299GSM7433311GSM7433300GSM7433305GSM7433306GSM7433303GSM7433304GSM7433309GSM7433307GSM743330824676233727Homo sapiens